All Photos(1)

46945

Sigma-Aldrich

Fluorescein isothiocyanate–dextran

average mol wt 70,000, (FITC:Glucose = 1:250)

Synonym(s):
FITC-Dextran 70, FITC–Dextran
CAS Number:
MDL number:
NACRES:
NA.32

Quality Level

biological source

synthetic

conjugate

FITC conjugate

assay

(FITC:Glucose = 1:250)

form

powder

mol wt

average mol wt 70,000

extent of labeling

~0.004 mol/mol FITC glucose

solubility

H2O: 50 mg/mL, hazy, orange to very deep orange

fluorescence

λex 492 nm; λem 518 nm in ethanol

application(s)

cell analysis

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Application

Fluorescein isothiocyanate–dextran (FITC-Dextran 70) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-Dextran 70 may be used to study the capacity, selectivity and efficiency of encapsulation and release by drug delivery vehicles.
Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

Other Notes

Internalisation of FITC and FITC-dextran by suspension cultured plant cells; In the study of fluid pinocytosis in leukocytes

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Misty R Riddle et al.
Developmental biology, 441(2), 285-296 (2018-06-09)
Through the course of evolution, the gastrointestinal (GI) tract has been modified to maximize nutrient absorption, forming specialized segments that are morphologically and functionally distinct. Here we show that the GI tract of the Mexican tetra, Astyanax mexicanus, has distinct
Use of horseradish peroxidase and fluorescent dextrans to study fluid pinocytosis in leukocytes.
J M Oliver et al.
Methods in enzymology, 108, 336-347 (1984-01-01)
L. Cole et al.
Journal of Cell Science, 96, 721-721 (1990)
Guangxiang Zang et al.
BMC cancer, 15, 234-234 (2015-04-18)
Shb is a signaling protein downstream of vascular endothelial growth factor receptor-2 and Shb deficiency has been found to restrict tumor angiogenesis. The present study was performed in order to assess metastasis in Shb deficiency using B16F10 melanoma cells. B16F10
Siegfried Weisenburger et al.
Cell, 177(4), 1050-1066 (2019-04-16)
Calcium imaging using two-photon scanning microscopy has become an essential tool in neuroscience. However, in its typical implementation, the tradeoffs between fields of view, acquisition speeds, and depth restrictions in scattering brain tissue pose severe limitations. Here, using an integrated

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service