Merck
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49781

Sigma-Aldrich

Glycerol solution

83.5-89.5% (T)

Synonym(s):
1,2,3-Propanetriol
Linear Formula:
HOCH2CH(OH)CH2OH · aq
CAS Number:
Molecular Weight:
92.09 (anhydrous basis)
Beilstein:
635685
EC Number:
MDL number:
PubChem Substance ID:

assay

83.5-89.5% (T)

form

viscous liquid

technique(s)

MALDI-MS: suitable

impurities

10.5-16.5% water

ign. residue

≤0.01% (as SO4)

bp

182 °C/20 mmHg (lit.)

density

1.252 g/mL at 25 °C (lit.)

SMILES string

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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General description

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.

Application

Glycerol solution has been used:
  • in the preparation of blood mimicking fluid
  • in epidermis mimicking films
  • as a constituent of nuclei storage buffer

Biochem/physiol Actions

Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.
Glycerol has been used as
  • a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
  • a fuel during designing enzymatic biofuel cell.
  • a liquid composite matrix with 4-HCCA and 3-amino­quinoline for analysis of neutral and acidic glycans.
  • a matrix for fast atom bombardment MS.
  • may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.

Other Notes

Substrate for the assay of glycerokinase; glycerol dehydratase; glycerol oxidase

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

320.0 °F - closed cup

Flash Point(C)

160 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Glycerol oxidase from Aspergillus japonicus.
T Uwajima et al.
Methods in enzymology, 89 Pt D, 243-248 (1982-01-01)
Automated end-to-end blood testing at the point-of-care: Integration of robotic phlebotomy with downstream sample processing
Balter ML, et al.
Technology, 1-8 (2018)
Multilayered tissue mimicking skin and vessel phantoms with tunable mechanical, optical, and acoustic properties
Chen AI, et al.
Medical Physics, 43(6), 3117-3131 (2016)
Glycerol dehydratase from Aerobacter aerogenes.
B C Johnson et al.
Methods in enzymology, 42, 315-323 (1975-01-01)
H.U. Bergmeyer, ed.
Methods of Enzymatic Analysis, 2, 216-216 (1983)

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