Merck
All Photos(4)

50046

Sigma-Aldrich

Glycine

BioUltra, for molecular biology, ≥99.0% (NT)

Synonym(s):
Aminoacetic acid, Aminoethanoic acid, Glycocoll
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

grade

for molecular biology

Quality Level

product line

BioUltra

Assay

≥99.0% (NT)

form

crystalline

impurities

DNases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected

ign. residue

≤0.05% (as SO4)

loss

≤0.05% loss on drying, HV, 20-26 °C

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤200 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

NCC(O)=O

λ

1 M in 1 M HCl

UV absorption

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

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This Item
33226G5417G7403
Glycine BioUltra, for molecular biology, ≥99.0% (NT)

Sigma-Aldrich

50046

Glycine

Glycine puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance)

Sigma-Aldrich

33226

Glycine

Glycine

SAFC

G5417

Glycine

Glycine BioXtra, ≥99% (titration)

Sigma-Aldrich

G7403

Glycine

grade

for molecular biology

grade

-

grade

-

grade

-

product line

BioUltra

product line

-

product line

-

product line

BioXtra

assay

≥99.0% (NT)

assay

99.7-101% (calc. to the dried substance)

assay

≥98.5%

assay

≥99% (titration)

form

crystalline

form

crystalline powder

form

crystalline powder

form

powder

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

impurities

≤0.001% heavy metals (as Pb), ≤0.02% ammonium (NH4), ≤0.1% water (Karl Fischer), ≤1.0% ninhydrin-positive substances

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

impurities

Insoluble matter, passes filter test

color

white

color

-

color

-

color

white

Application

Glycine has been used as a component of the viral extraction mixture for adenovirus viral extraction.

Biochem/physiol Actions

Glycine is a non-essential amino acid. It is involved in the synthesis of purines, serine and porphyrins. Glycine-gated channels mediate the influx of calcium through cell membranes. It also acts as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. In cancer cells, the synthesis of glycine might be increased due to increased demand for the amino acid.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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