EPS001

Sigma-Aldrich

HAT Activator, CTPB

A potent activator of HAT (histone acetyltransferase)

Synonym(s):
CTPB, CTPB (enzyme activator), CTPB (enzyme inhibitor), N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide, Benzamide, N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl
Empirical Formula (Hill Notation):
C31H43ClF3NO2
CAS Number:
Molecular Weight:
554.13

Quality Level

assay

≥97% (H-NMR)

storage condition

desiccated
protect from light

color

white to off-white

solubility

DMSO: soluble

storage temp.

−20°C

Related Categories

General description

(N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide) or CTPB, which is a non-polar compound, has been shown to enhance the neurite growth and survival of neuronal cell lines.
A potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Certificate of Analysis

Certificate of Origin

Small molecule modulators of histone acetyltransferase p300
Karanam B et al.
The Journal of Biological Chemistry (2003)
A small molecule activator of p300/CBP histone acetyltransferase promotes survival and neurite growth in a cellular model of Parkinson?s disease
Shane VH et al.
Neurotoxicity Research, 30(3), 510-520 (2016)
null

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service