Merck
All Photos(3)

F3388

Sigma-Aldrich

Ferric citrate

BioReagent, suitable for cell culture

Synonym(s):
Iron(III) citrate, Iron(III) citrate hydrate
Empirical Formula (Hill Notation):
C6H5FeO7
CAS Number:
Molecular Weight:
244.94
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

biological source

synthetic (organic)

Quality Level

product line

BioReagent

technique(s)

cell culture | mammalian: suitable

solubility

hot water: 0.01 g/mL, clear, orange-yellow

shipped in

ambient

storage temp.

room temp

SMILES string

OC12CC(=O)O[Fe](OC(=O)C1)OC2=O

InChI

1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3

InChI key

NPFOYSMITVOQOS-UHFFFAOYSA-K

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Application

Ferric citrate provides a source of iron used in cell culture applications. It provides iron in a less toxic form than free iron salts. Ferric citrate has been used as medium supplement in human osteosarcoma cell (U2OS) culture, human embryonic kidney (HEK293) cells and adult primary cardiomyocytes.

Packaging

250 g in poly bottle
1 kg in poly bottle

Biochem/physiol Actions

Ferric citrate is used as a component of protein-free medium. It is used as a substitute for transferrin in mouse hybridomas culture. Ferric citrate enhances IgM production. It indirectly stimulates the mitogen-activated protein kinase (MAPK) by favoring high amphiregulin oncoprotein levels in colon cancer.  Ferric citrate is effective in binding to phosphate in patients with dialysis-dependent chronic kidney disease.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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