FAMLS

Sigma-Aldrich

Fatty Acid Metabolite Library of Standards

Supplied by IROA Technologies

Synonym(s):
Mass Spectrometry Metabolite Library

shipped in

dry ice

storage temp.

−20°C

General description

FAMLS (Fatty Acid Metabolite Library of Standards) is a collection of high quality fatty acids that span a broad range of primary metabolism. These are high purity (>95%) compounds supplied in an economical, ready to-use format. The library is most commonly used to provide retention times and spectra for key metabolic compounds, help optimize analytical mass spectrometry protocols, and qualify and quantify mass spectrometry sensitivity and limit of detection.
Key primary metabolites and intermediates covering key metabolic pathways, including the following classes of fatty acids:
  • Short chain
  • Medium chain
  • Long chain
  • Very long chain
  • Saturated and unsaturated
  • Branched

Application

FAMLS (Fatty Acid Metabolite Library of Standards) is a collection of high quality small biochemical molecules in an economical, ready-to-use format. This library of standards is most commonly used for metabolite qualification and quantification for MS. Compounds can either be used as standards and injected individually or a strategy may be employed to pool compounds to allow multiple mixtures to be analyzed per injection.

Features and Benefits

96 unique small molecule fatty acid metabolites covering key metabolic pathways.

To view a complete list of compounds in the library visit the FAMLS Plate Map

The complete plate map with Name, parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Substance ID are provided with the software download.

Preparation Note

Compounds are pre-weighed and provided at 5 ug per well, enough for multiple injections. Arranged in a 96-well polypropylene plate with alphanumerically assigned positions. Discovery software is provided to help construct libraries, useful for metabolomic compound ID.

Other Notes

MLSDiscovery software tool is provided to support the extraction, manipulation, and storage of the data generated when using the FAMLS and other authentic libraries of metabolite standards supplied by IROA Technologies. Software comes with user manual and training videos.

To download the software package, visit sigma.com/mlsdiscovery.

To view the MLSDiscovery Video visit: MLSDiscovery Tutorial Video.

Legal Information

FAMLS is a trademark of IROA Technologies LLC
MLSDiscovery is a trademark of IROA Technologies LLC

signalword

Danger

hazcat

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 3 - Met. Corr. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

3 - Flammable liquids

Certificate of Analysis

Certificate of Origin

Charles M Nichols et al.
Analytical chemistry, 90(24), 14484-14492 (2018-11-20)
In this work, we established a collision cross section (CCS) library of primary metabolites based on analytical standards in the Mass Spectrometry Metabolite Library of Standards (MSMLS) using a commercially available ion mobility-mass spectrometer (IM-MS). From the 554 unique compounds...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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