All Photos(4)

FD70S

Sigma-Aldrich

Fluorescein isothiocyanate–dextran

average mol wt 60,000-76,000

Synonym(s):
FITC–Dextran
CAS Number:
MDL number:
NACRES:
NA.25

Quality Level

biological source

bacterial (Leuconostoc mesenteroides)

conjugate

FITC conjugate

form

powder

mol wt

average mol wt 60,000-76,000

extent of labeling

0.003-0.020 mol FITC per mol glucose

solubility

H2O: 25 mg/mL, clear to slightly hazy, yellow-orange

storage temp.

2-8°C

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Application

FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination. Small FITC-dextrans are also used to measure processes such as endocytosis and cell junction permeability. FITC-dextran 70 kDa (FD-70) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. FD-70 may be used in microvascular and cell monolayer permeability studies.
Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

Packaging

1, 5 g in poly bottle
100, 250 mg in poly bottle

Linkage

Similar to FD-70, but produced by Sigma.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Gabriela Hurtado-Alvarado et al.
PloS one, 11(11), e0167236-e0167236 (2016-11-29)
Chronic sleep restriction induces blood-brain barrier disruption and increases pro-inflammatory mediators in rodents. Those inflammatory mediators may modulate the blood-brain barrier and constitute a link between sleep loss and blood-brain barrier physiology. We propose that adenosine action on its A2A
Maira Carrillo et al.
Medicine, 97(39), e12392-e12392 (2018-10-04)
Imaging of placental tissues is a difficult task, because of specific for this organ complex multicellular and 3D tissue structure. The tissue clearing systems (X-CLARITY) system is a valuable tool for the examining the expression of molecular pathways in whole
Michael J Shirey et al.
Journal of neurophysiology, 114(1), 309-322 (2015-05-15)
Changes in brain temperature can alter electrical properties of neurons and cause changes in behavior. However, it is not well understood how behaviors, like locomotion, or experimental manipulations, like anesthesia, alter brain temperature. We implanted thermocouples in sensorimotor cortex of
Ting Su et al.
International journal of pharmaceutics, 555, 291-302 (2018-11-25)
Polyphosphates are important polyanionic electrolytes that play a major role in stabilization and consolidation of colloids surface and interior microstructures. In this study, the polyelectrolyte complexes (PEC) microcapsules (sodium cellulose sulfate-chitosan hydrochloride, sample 1), and the patched ones via sodium
Chen-Mei Chen et al.
International journal of molecular sciences, 21(10) (2020-05-18)
Zinc oxide nanoparticles (ZnONPs) are frequently encountered nanomaterials in our daily lives. Despite the benefits of ZnONPs in a variety of applications, many studies have shown potential health hazards of exposure to ZnONPs. We have shown that oropharyngeal aspiration of

Related Content

Fluorescein Isothiocyanate-Dextran

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

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