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Guanosine 5′-diphosphate sodium salt

Type I, ≥96% (HPLC)

Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:

Quality Level


Type I


≥96% (HPLC)

shipped in

dry ice

storage temp.


SMILES string




InChI key


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Guanosine 5′-diphosphate sodium salt has been used:
  • in GTP-γ-35S functional assays
  • in Y1 agonist-stimulated [35S]- guanosine-5′-O-(3-thio)triphosphate (GTPγS) functional binding
  • in the expression and purification of recombinant proteins


10 mg in glass bottle
25, 100, 500 mg in poly bottle
1 g in poly bottle

Biochem/physiol Actions

Guanosine 5′-diphosphate (GDP) is the diphosphate nucleoside of the purine guanine. GDP and GTP are involved in and may be used to study cell signaling via G-coupled protein receptors (GCPR) and guanine nucleotide exchange factors (GEF) and a variety of GTPases.

Storage Class Code

11 - Combustible Solids

WGK Germany


Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

María-de-Los-Angeles Andrade-Oliva et al.
Environmental toxicology and pharmacology, 60, 58-65 (2018-04-17)
Male Sprague-Dawley rats (8-9 weeks-old) were exposed for three days (acute exposure) or eight weeks (subchronic exposure) to purified air or concentrated ambient fine particles, PM2.5 (≤2.5 μm; 15 to 18-fold of ambient air; 370-445 μg/m3). In membranes from rat prefrontal cortex...
Neuropeptide Y promotes neurogenesis in murine subventricular zone
Agasse F, et al.
Stem Cells, 26(6), 1636-1645 (2008)
A p120 catenin isoform switch affects Rho activity, induces tumor cell invasion, and predicts metastatic disease
Yanagisawa M, et al.
The Journal of Biological Chemistry, 283(26), 18344-18354 (2008)
N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT 1A agonist, as a putative mediator of quetiapine's antidepressant activity
Jensen N H, et al.
Neuropsychopharmacology, 33(10), 2303-2303 (2008)
Viola Spahn et al.
Scientific reports, 8(1), 8965-8965 (2018-06-14)
Novel pain killers without adverse effects are urgently needed. Opioids induce central and intestinal side effects such as respiratory depression, sedation, addiction, and constipation. We have recently shown that a newly designed agonist with a reduced acid dissociation constant (pKa)...


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Get to know the Tricarboxylic acid (TCA) cycle to better inform your research in biochemistry, metabolomics, or related fields concerned with this metabolic pathway and its enzymes, by-products, or intermediates.


HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC

HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC

LC MS Analysis of Nucleotides Effect of pH

ZIC-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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