All Photos(3)

L1750

Sigma-Aldrich

L-(+)-Lactic acid

≥98%

Synonym(s):
Sarcolactic acid, (S)-2-Hydroxypropionic acid
Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
Beilstein:
1720251
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥98%

Mode of action

cell membrane | interferes

antibiotic activity spectrum

Gram-negative bacteria

storage temp.

2-8°C

SMILES string

C[C@H](O)C(O)=O

InChI

1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1

InChI key

JVTAAEKCZFNVCJ-REOHCLBHSA-N

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General description

L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81).

Application

Lactic acid has been used:
  • as a component in substrate solution II for lactate dehydrogenase reaction
  • as an additive in storage solution A
  • as a supplement in the artificial gastric juice preparation for evaluation of degree of resistance Lactobacillus to the gastric stresses

Packaging

10, 100 g in glass bottle

Biochem/physiol Actions

L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.

pictograms

Corrosion

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 1

Flash Point F

230.0 °F - closed cup

Flash Point C

110.00 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Mastoparan as a G protein activator
Animal Toxins: Facts and Protocols, 120-121 (2000)
International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands
Davenport AP, et al.
Pharmacological Reviews, 65(3), 967-986 (2013)
A History of Lactic Acid Making: A Chapter in the History of Biotechnology (1990)
Cell-free transcription of SV40
SV40 protocols, 73-73 (2001)
The isolation, identification and analyzes of Lactobacillus genus bacteria with probiotic potential
Advances in Microbiology, Infectious Diseases and Public Health, 73-73 (2016)

Protocols

LC/MS Analysis of Lactic Acid Enantiomers in Urine on Astec® CHIROBIOTIC® R

Separation of L-(+)-Lactic acid, analytical standard; D-(−)-Lactic acid, 93-107%

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