If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
L8912
L-Leucine
98.5-101.0%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications
Synonym(s):
(S)-Leucine, (S)-2-Amino-4-methylpentanoic acid
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| Pack Size | SKU | Availability | Price |
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About This Item
Product Name
L-Leucine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
biological source
non-animal source
Quality Level
agency
USP/NF, meets EP testing specifications, meets JP testing specifications, meets USP testing specifications
assay
98.5-101.0%
form
powder
optical activity
[α]20/D 14.9 to 16.0°, c = 4 in 6 M HCl, [α]25/D 14.9 to 17.3 °, c = 4 in 6 M HCl
quality
meets EP, JP, USP testing specifications
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
mp
>300 °C (lit.)
solubility
1 M HCl: 50 mg/mL
cation traces
As: ≤1 ppm, Fe: ≤10 ppm, NH4+: <0.02%, heavy metals: ≤10 ppm
application(s)
peptide synthesis
pharmaceutical (small molecule)
functional group
amine, carboxylic acid
storage temp.
room temp
SMILES string
CC(C)C[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChI key
ROHFNLRQFUQHCH-YFKPBYRVSA-N
General description
Application
- as a hypertrophic agent to monitor its effects on myotubes.
- as a component of PMG media for culturing yeast.
- in myotube protein synthesis analysis in skeletal muscle cells.
- to study its effects on hepatic lipid metabolism.[2]
Biochem/physiol Actions
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| form powder | form - | form powder | form - |
| assay 98.5-101.0% | assay - | assay ≥98% (HPLC) | assay - |
| technique(s) cell culture | mammalian: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) ligand binding assay: suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable |
| functional group amine, carboxylic acid | functional group - | functional group - | functional group - |
| storage temp. room temp | storage temp. 2-8°C | storage temp. - | storage temp. 20-25°C |
| cation traces As: ≤1 ppm, NH4+: <0.02%, Fe: ≤10 ppm, heavy metals: ≤10 ppm | cation traces - | cation traces - | cation traces - |
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L8912-25G | 04061833966280 |
| L8912-10MG | 04061833966266 |
| L8912-1KG | 04061833966273 |
| L8912-100G | 04061835546558 |
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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