N9876

4-Nitrophenyl butyrate

≥98%

• Synonym(s): p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
• Empirical Formula (Hill Notation): C₁₀H₁₁NO₄
• CAS Number: 2635-84-9
• Molecular Weight: 209.20
• Beilstein: 1879729
• MDL number: MFCD00047734
• PubChem Substance ID: 24897915
• NACRES: NA.83

Properties

• Quality Level: 200
• Assay: ≥98%
• form: liquid
• density: 1.19 g/mL at 20 °C (lit.)
• storage temp.: −20°C
• SMILES string: CCCC(=O)Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C10H11NO4/c1-2-3-10(12)15-9-6-4-8(5-7-9)11(13)14/h4-7H,2-3H2,1H3
• InChI key: DVDUMIQZEUTAGK-UHFFFAOYSA-N

Description

General description

4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.

Application

4-nitrophenyl butyrate has been used:

• as a substrate for esterase activity in monocyte-derived macrophage cell line in response to polyethylene
• as a substrate for mycobacterial phospholipase A and mycobacterial cutinase activity
• as a substrate to determine the effect of buffers and solvents on human carboxylesterase

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves