All Photos(2)

P8877

Sigma-Aldrich

D-(−)-3-Phosphoglyceric acid disodium salt

≥93%, powder

Synonym(s):
(−)-Disodium D-3-phosphoglycerate, D-Glycerate 3-phosphate disodium salt
Empirical Formula (Hill Notation):
C3H5Na2O7P
CAS Number:
Molecular Weight:
230.02
Beilstein:
3767836
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

biological source

synthetic (inorganic)

assay

≥93%

form

powder

color

white

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

greener alternative category

Re-engineered

storage temp.

−20°C

SMILES string

[Na+].[Na+].O[C@H](COP(O)([O-])=O)C([O-])=O

InChI

1S/C3H7O7P.2Na/c4-2(3(5)6)1-10-11(7,8)9;;/h2,4H,1H2,(H,5,6)(H2,7,8,9);;/q;2*+1/p-2/t2-;;/m1../s1

InChI key

RGCJWQYUZHTJBE-YBBRRFGFSA-L

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Application

D-(-)-3-Phosphoglyceric acid disodium salt has been used in a study to assess the phosphorylation of glyceric acid in aqueous solution. It has also been used in a study to characterize a glutathione- and NAD-dependent arsenate reduction linked to glycolysis.

Packaging

10 mg in glass bottle
1, 5 g in glass bottle

Biochem/physiol Actions

3-Phosphoglyceric acid is an intermediate in glycolysis. It also a precursor in the formation of serine.

pictograms

Exclamation markHealth hazard

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK Germany

WGK 3

Certificate of Analysis

Certificate of Origin

Balázs Németi et al.
Toxicological sciences : an official journal of the Society of Toxicology, 85(2), 847-858 (2005-03-25)
Reduction of arsenate (AsV) to the more toxic arsenite (AsIII) is of high toxicological importance, yet in vivo relevant enzymes involved have not been identified. Purine nucleoside phosphorylase (PNP) is an efficient AsV reductase in vitro, but its role in...
V Kolb et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 26(1), 7-13 (1996-02-01)
The phosphorylation of glyceric acid is an interesting prebiotic reaction because it converts a simple, potentially prebiotic organic molecule into phosphate derivatives that are central to carbohydrate metabolism. We find that 0.05 M glyceric acid in the presence of 0.5...
Liangchun Yang et al.
Nature communications, 5, 4436-4436 (2014-07-16)
Increasing evidence suggests the important role of metabolic reprogramming in the regulation of the innate inflammatory response, but the underlying mechanism remains unclear. Here we provide evidence to support a novel role for the pyruvate kinase M2 (PKM2)-mediated Warburg effect...

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