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RAB0319

Sigma-Aldrich

Human IL-8 / CXCL8 ELISA Kit

for serum, plasma, cell culture supernatant and urine

NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

application(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum
sample type plasma

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL8(3576)

General description

Interleukin-8 (IL-8)/CXCL8 is an important chemoattractant cytokine and activator of neutrophils. It is liberated from endothelial cells, gingival fibroblasts, neutrophils, monocytes and phagocytes in the gingival crevice. IL-8 belongs to the CXC subfamily. This gene is located on human chromosome 4q13.3.

Immunogen

Recombinant Human IL-8

Application

Human IL-8 /CXCL8 ELISA Kit has been used:
  • to quantify IL?8 from A549 cell culture medium
  • in quantitative measurement of IL-8 from cell culture supernatant
  • in supernates of acute lung infection model (ALIM)

Biochem/physiol Actions

Interleukin-8 (IL-8)/CXCL8 participates in the progression of peripheral muscle weakness in individuals with COPD (chronic obstructive pulmonary disease). It helps in the transport of neutrophils across endothelium, pulmonary epithelium and fibroblasts.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)

  • RABSTOP3ELISA Stop Solution (Item I)

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)

  • RABWASH420X Wash Buffer (Item B)

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

Certificate of Analysis

Certificate of Origin

BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses
Kokkola T, et al.
Chembiochem, 16(14), 1997-2001 (2015)
The chemokine and chemokine receptor superfamilies and their molecular evolution
Zlotnik A, et al.
Genome Biology, 7(12), 1-11 (2006)
Effect and mechanism of calpains on pediatric lobar pneumonia.
Yin G, et. al.
Bioengineered, 8, 374-374 (2017)
Association between interleukin-8 levels and chronic periodontal disease: A PRISMA-compliant systematic review and meta-analysis
Finoti LS, et al.
Medicine, 96(22) (2017)
Effects of rilpivirine, 17 beta-estradiol and beta-naphthoflavone on the inflammatory status of release of adipocytokines in 3T3-L1 adipocytes in vitro
Behl S, et al.
Molecular Biology Reports, 46(3), 2643-2655 (2019)

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