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T3251

Sigma-Aldrich

(±)-α-Tocopherol

synthetic, ≥96% (HPLC)

Synonym(s):

DL-all-rac-α-Tocopherol, Vitamin E

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5 G
CHF 38.20
25 G
CHF 111.00
100 G
CHF 236.00
500 G
CHF 773.00

CHF 38.20

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5 G
CHF 38.20
25 G
CHF 111.00
100 G
CHF 236.00
500 G
CHF 773.00

About This Item

Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
10191-41-0
Molecular Weight:
430.71
Beilstein:
94012
EC Number:
233-466-0
MDL number:
MFCD00006848
UNSPSC Code:
12352205
eCl@ss:
34058016
PubChem Substance ID:
24900118
NACRES:
NA.77

CHF 38.20

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biological source

synthetic

Quality Level

200

Assay

≥96% (HPLC)

form

liquid

technique(s)

HPLC: suitable

color

faint brown to brown
 yellow to very dark yellow

solubility

H2O: insoluble
acetone: miscible
chloroform: miscible
ethanol: miscible
vegetable oils: miscible

density

0.950 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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This Item
47783V-020PHR1031
(±)-α-Tocopherol synthetic, ≥96% (HPLC)

T3251

(±)-α-Tocopherol

(±)-α-Tocopherol analytical standard

47783

(±)-α-Tocopherol

(±)−α−Tocopherol (Vitamin E) solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

V-020

(±)−α−Tocopherol (Vitamin E) solution

Alpha Tocopherol Pharmaceutical Secondary Standard; Certified Reference Material

PHR1031

Alpha Tocopherol

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

biological source

synthetic

biological source

-

biological source

-

biological source

-

assay

≥96% (HPLC)

assay

-

assay

-

assay

-

form

liquid

form

liquid

form

liquid

form

-

solubility

H2O: insoluble, chloroform: miscible, vegetable oils: miscible, acetone: miscible, ethanol: miscible

solubility

-

solubility

-

solubility

-

storage temp.

2-8°C

storage temp.

-10 to -25°C

storage temp.

−70°C

storage temp.

2-8°C

Application

(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.

Biochem/physiol Actions

Tocopherols (vitamin E) comprise of a series (α, β, γ and δ) of chiral compounds that differ by the methylation degree of the phenol moiety of the chromanol ring. They function as lipid soluble antioxidants and protect cell membranes from oxidative damage. α-tocopherols are favorably absorbed by humans and their nicotinate salts can function as vitamin E supplements. Studies have also reported that vitamin E can prevent cell damage caused by pharmacologically induced epilepsy in rats.

Preparation Note

(±)-α-Tocopherol is miscible with chloroform, ethanol, ether, acetone, and vegetable oils. However, it is practically insoluble in water. (±)-α-Tocopherol is unstable under alkaline conditions.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX9780
0000457117
0000457117
0000415404
0000415404

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