Merck
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T5251

Sigma-Aldrich

D-(+)-Trehalose dihydrate

from Saccharomyces cerevisiae, ≥98.5% (HPLC)

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Synonym(s):
α,α-Trehalose dihydrate, D-Trehalose dihydrate, α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
Empirical Formula (Hill Notation):
C12H22O11 · 2H2O
CAS Number:
Molecular Weight:
378.33
Beilstein:
5322018
EC Number:
MDL number:
PubChem Substance ID:

biological source

Saccharomyces cerevisiae

Quality Level

Assay

≥98.5% (HPLC)

form

powder

optical activity

[α]/D 174 to 182 °, c = 1.0% (w/v) in water

technique(s)

HPLC: suitable
cryopreservation: suitable

mp

97-99  °C

application(s)

agriculture
agriculture
cell analysis
genomic analysis
life science and biopharma

SMILES string

[H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

InChI key

DPVHGFAJLZWDOC-PVXXTIHASA-N

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This Item
90210T0167625625
D-(+)-Trehalose dihydrate suitable for microbiology, ≥99.0%, composed of two α-glucose units that is used as a protectant, stabilizer and to support proper folding

Millipore

90210

D-(+)-Trehalose dihydrate

Trehalose, Dihydrate Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro.

Millipore

625625

Trehalose, Dihydrate

assay

≥98.5% (HPLC)

assay

≥99.0% (HPLC)

assay

≥99%

assay

≥97.5% (by Assay)

form

powder

form

powder

form

powder

form

solid

technique(s)

HPLC: suitable, cryopreservation: suitable

technique(s)

-

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

-

mp

97-99  °C

mp

-

mp

-

mp

-

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

100

General description

D-(+)-Trehalose, a disaccharide, acts as a chemical chaperone and serves as a carbohydrate reserve in microorganisms. It functions as an osmolyte, safeguarding cells against various environmental stresses. Further, it also plays a crucial role in protein stabilization during freeze drying, making it a valuable asset in the areas of biochemical, cell culture, and excipient research

Application

  • Use as a cryoprotectant in a variety of cell freezing media
  • Used in excipeint research

Biochem/physiol Actions

Trehalose is a non-reducing sugar formed from two glucose units joined by a 1-1 alpha bond. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.

Features and Benefits

  • Prepared from Saccharomyces cerevisiae
  • Suitable for use with HPLC and GC-MS(4)

Preparation Note

Prepared by the modified procedure of Payen, R., Can. J. Res., 27B, 749 (1949).

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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