Skip to Content
Merck
HomeProductsCell Culture & Analysis3D Cell Culture Techniques

3D Cell Culture Techniques

A three dimensional cell culture

Cells naturally grow and differentiate in 3D environments. Improved 3D cell culture models can more accurately replicate the native tissue environment to provide meaningful scientific conclusions. We offer a broad portfolio of solutions for 3D cell culture including products for supporting spheroid growth, scaffolds, hydrogels, organoids, ULA plates, and other cultureware.  

Explore by Category

Close-up photo of a transparent, gel-like substance neatly contained within a circular glass dish held by a metal spoon, a sample of a hydrogel

Hydrogels

Cells embedded in 3D hydrogels can polarize, differentiate and have functional attributes that more closely resemble physiological tissues. Choose naturally derived hydrogels or reconstitute a hydrogel from synthetic materials to develop predictive cellular models.

Scaffolds for 3D Cell Culture

Cells grown on structural scaffolds engineered to mimic the ECM can be powerful, predictive models of physiological processes. Our wide range of advanced 3D cell culture scaffolds includes nanofiber, collagen, polystyrene, and polycaprolactone materials.

Scanning electron microscope image depicting clusters of microbial cells adhering to a fibrous network, displayed in monochrome for detailed texture analysis.

Explore More Categories

Fluorescence microscopy image showing the intricate, glowing green patterns of cells, highlighting the detailed cellular structure.
Organoids

Organoids are in vitro models that closely replicate the complex physiology of native tissues while also being accessible, reproducible, and scalable like traditional culture methods. Choose colon organoids, lung organoid culture systems, and patient-derived organoids from our biobank.

View Products

Shop Products

plates (24)

kits (18)

inserts (10)

dishes (4)

media (4)

media supplements (3)

SynVivo (31)

Nanofiber Solutions (18)

Bio Byblos Biomedical (16)

Scaffdex (11)

3D Biotek (10)

Lena Biosciences (4)

polycaprolactone (PCL) (13)

polycarbonate (10)

polystyrene (5)
Sort by Relevance
Showing 1-20 of 137
Change View
Showing 1-20 of 137
SynVivo SynTumour 3D cancer model chip, microvascular network configuration, 8 um pillar
VIV105015STU3

SynVivo SynTumour 3D cancer model chip, microvascular network configuration, 8 um pillar

case of 3 ea

ECM Gel from Engelbreth-Holm-Swarm murine sarcoma
E1270

ECM Gel from Engelbreth-Holm-Swarm murine sarcoma

liquid, BioReagent, suitable for cell culture

3dGRO<SUP>®</SUP> R-Spondin-1 Conditioned Media Supplement
SCM104

3dGRO® R-Spondin-1 Conditioned Media Supplement

Alternative stem cell media supplement to purified recombinant R-Spondin-1 protein for organoid cultures.

MaxGel<SUP>™</SUP> ECM
E0282

MaxGel ECM

mixture, liquid

3dGRO<SUP>®</SUP> Human Colon Organoid Expansion Medium
SCM304

3dGRO® Human Colon Organoid Expansion Medium

Complete serum-free organoid media for the expansion and long-term 3D culture of human intestinal colon organoids.

3dGRO<SUP>®</SUP> Human iPSC Derived Colon Organoids
SCC300

3dGRO® Human iPSC Derived Colon Organoids

ECM Gel from Engelbreth-Holm-Swarm murine sarcoma
E6909

ECM Gel from Engelbreth-Holm-Swarm murine sarcoma

growth-factor reduced, without phenol red, liquid, BioReagent, suitable for cell culture

PureCol<SUP>™</SUP> EZ Gel solution
5074

Bovine Collagen Type I

from bovine skin, liquid, 5 mg/mL, suitable for cell culture, used for 3D Hydrogel formation, PureCol EZ Gel

DMEM/F-12 PLUS Basal Medium
SCM162

DMEM/F-12 PLUS Basal Medium

Advanced DMEMF12 basal media used in low-serum or serum-free media formulations including stem cell and 3D organoid cell cultures.

R-Spondin1 expressing 293T Cell Line
SCC111

R-Spondin1 expressing 293T Cell Line

Human

CellCrown<SUP>™</SUP> inserts
Z682004

CellCrown inserts

96 well plate inserts, 8-well strips, sterile

CellCrown<SUP>™</SUP> inserts
Z681962

CellCrown inserts

48 well plate inserts, 6-well strips, sterile

3dGRO<SUP>®</SUP> Organoid Freeze Medium
SCM301

3dGRO® Organoid Freeze Medium

Optimized cryopreservation media for multiple organoids cell types.

3dGRO<SUP>®</SUP> Organoid Dissociation Reagent
SCM300

3dGRO® Organoid Dissociation Reagent

Chemically defined enzyme-free organoid dissociation solution.

TrueGel3D Hydrogel Kits
TRUE7

TrueGel3D Hydrogel Kits

SLO-DEXTRAN, allow cell recovery, CD cell-degradable crosslinker

CellCrown<SUP>™</SUP> inserts
Z742381

CellCrown inserts

24 well plate inserts, sterile

Nanofiber multiwell plate, with aligned nanofibers
Z694541

Nanofiber multiwell plate, with aligned nanofibers

size 96 wells

Nanofiber multiwell plate, with aligned nanofibers
Z694533

Nanofiber multiwell plate, with aligned nanofibers

size 24 wells

Nanofiber chamber slides
Z694576

Nanofiber chamber slides

8 chamber slide, aligned nanofibers

TrueGel3D Hydrogel Kits
TRUE1

TrueGel3D Hydrogel Kits

CD cell-degradable crosslinker and RGD peptide

You have viewed 1-20 of 137 results

Sign In To Continue

To continue reading please sign in or create an account.

Don't Have An Account?