Merck
Search Within

111-27-3

Applied Filters:
Keyword:'111-27-3'
Showing 1-27 of 27 results for "111-27-3" within Papers
Percival D Sampaio-Barros et al.
Rheumatology international, 28(5), 483-486 (2007-08-25)
This retrospective study analyzed the HLA-B 27 alleles in a group of 20 consecutive patients with the diagnosis of Reiter syndrome (RS) followed in a tertiary referral university hospital in Brazil, during the period 1990-2006, and compared the data with
Panteleimon J Marsouvanidis et al.
Cancer biotherapy & radiopharmaceuticals, 29(9), 359-367 (2014-10-07)
Gastrin-releasing peptide receptors (GRPR) and GRP-derived analogs have attracted attention due to high receptor expression in frequently occurring human neoplasia. The authors recently synthesized a series of GRPR-affine peptide analogs based on the 27-mer GRP and derivatized with the DOTA
Neeta Pandit-Taskar et al.
EJNMMI research, 5, 28-28 (2015-05-20)
J591 is a monoclonal antibody that targets the external domain of the prostate-specific membrane antigen (PSMA). Besides prostate cancer cells, it also targets the neovasculature of non-prostate solid tumors. We provide an analysis of the antibody mass-dose dependency of lesion
Eric Vejerano et al.
Environmental science & technology, 45(2), 589-594 (2010-12-09)
Previous studies have shown environmentally persistent free radicals (EPFRs) form when chlorine- and hydroxy-substituted benzenes chemisorb on Cu(II)O-containing surfaces under postcombustion conditions. This paper reports the formation of EPFRs on silica particles containing 5% Fe(III)(2)O(3). The EPFRs are formed by
Lianmin Chen et al.
Cell reports, 33(1), 108212-108212 (2020-10-08)
Bile acids (BAs) are implicated in the etiology of obesity-related conditions such as non-alcoholic fatty liver disease. Differently structured BA species display variable signaling activities via farnesoid X receptor (FXR) and Takeda G protein-coupled BA receptor 1 (TGR5). This study
Gloria E Mao et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 13(3), 383-390 (2004-03-10)
The development of prostatic intraepithelial neoplasia (PIN)-like lesions in the prostate-specific retinoid X receptor-alpha (RXRalpha) null mouse suggests that RXRalpha may protect against neoplasia. The purpose of this study was to characterize RXRalpha protein expression in human prostate to determine
R E Novy et al.
The Journal of biological chemistry, 266(25), 16917-16924 (1991-09-05)
Overlapping cDNA clones encoding a low M gamma human nonmuscle caldesmon isoform (HUM 1-CaD) span the entire coding region (538 amino acids) as well as 111 base pairs (bp) of 5'-noncoding and 1249 bp of 3'-noncoding region. Northern blot probes
Wolfgang Koechling et al.
British journal of clinical pharmacology, 70(4), 580-587 (2010-09-16)
Early studies on gonadotrophin-releasing hormone (GnRH) antagonists pointed out histamine-mediated anaphylactic reactions as a potential adverse effect of these drug candidates. In this study we have compared the histamine-releasing potential of four approved and marketed antagonists, degarelix, cetrorelix, abarelix and
Andrea N Leaf et al.
Medical oncology (Northwood, London, England), 20(2), 137-146 (2003-07-02)
This study, a phase III multicenter randomized trial opened by ECOG in April 1983 and closed in June 1986 was designed to evaluate whether a combination of doxorubicin and an intravenous formulation of diethylstilbestrol diphosphate (DES) was superior to doxorubicin
Hirohito Abe et al.
Journal of bone and mineral metabolism, 35(4), 412-418 (2016-08-24)
The purpose of this study was to clarify bone turnover marker levels in rapidly destructive coxopathy (RDC). Twenty patients with RDC (mean age, 72 ± 11 years; 3 men, 17 postmenopausal women), 111 with osteoarthritis (OA) (age, 60 ± 10 years; 15 men, 13 premenopausal women
Sara Marinelli et al.
BMC cancer, 14, 403-403 (2014-06-07)
Development of escape pathways from antiangiogenic treatments was reported to be associated with enhanced tumor aggressiveness and rebound effect was suggested after treatment stop. Aim of the study was to evaluate tumor response simulating different conditions of administration of antiangiogenic
Janusz K Rybakowski et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 144B(6), 820-823 (2007-03-22)
Both serotonin transporter and brain-derived neurotrophic factor (BDNF) genes have been previously implicated in the efficacy of lithium prophylaxis. The aim of the present study was to assess a possible interaction between serotonin transporter genotype (5HTTLPR) and BDNF Val66Met polymorphism
J J Lynch et al.
European journal of pharmacology, 364(2-3), 141-146 (1999-02-05)
The present study was conducted to characterize the development of tactile allodynia in the streptozotocin-induced rat model of diabetes, and to evaluate the antinociceptive effects of systemically administered morphine and the adenosine kinase inhibitor, 5'-deoxy-5-iodotubercidin (5'd-5IT) in this model. Rats
Soichiro Shibui et al.
Cancer chemotherapy and pharmacology, 71(2), 511-521 (2012-12-12)
Glioblastoma (GBM) is one of the worst cancers in terms of prognosis. Standard therapy consists of resection with concomitant chemoradiotherapy. Resistance to nimustine hydrochloride (ACNU), an alkylating agent, has been linked to methylguanine DNA methyltransferase (MGMT). Daily administration of procarbazine
Sinead Cuffe et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7(6), 963-972 (2012-05-17)
The staging of node-negative non-small-cell lung cancer is modified in the 7th edition TNM classification. Here, we pool data from the National Cancer Institute of Canada Clinical Trials Group JBR.10 trial and the Cancer and Leukemia Group B-9633 trial to
Jussara M do Carmo et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 317(4), R552-R562 (2019-08-15)
The main goal of this study was to compare the impact of total body leptin deficiency with neuronal-specific leptin receptor (LR) deletion on metabolic and cardiovascular regulation. Liver fat, diacylglycerol acyltransferase-2 (DGTA2), and CD36 protein content were measured in wild-type
Eun Jin Kim et al.
Biochemical genetics, 46(7-8), 506-519 (2008-05-28)
The solute carrier family 11 member 1 (SLC11A1) protein plays important roles in macrophage activation and displays pleiotropic effects on various macrophage functions, including the regulation of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and oxidative burst. Considering the important roles
Min Zhang et al.
Drug design, development and therapy, 14, 669-676 (2020-02-29)
This retrospective cohort study is to analyze the impacts of CYP2C19 polymorphism and clopidogrel dosing on in-stent restenosis (ISR) after coronary stenting. Totally, 111 patients were included, who underwent percutaneous coronary intervention (PCI) with drug-eluting stent. Patients received clopidogrel treatment
I Ia Tseĭmakh et al.
Terapevticheskii arkhiv, 85(3), 17-22 (2013-05-31)
To analyze the systemic manifestations of vascular endothelial damage, the activation of hemostatic and inflammatory responses in patients with an infectious inflammation-dependent exacerbation of chronic obstructive pulmonary disease (COPD). The paper provides the data of examinations of 111 patients with
S-J Yin et al.
Journal of clinical pharmacy and therapeutics, 37(3), 364-369 (2011-09-15)
Cytochrome P450 2C19 (CYP2C19) and CYP2D6 are important xenobiotic metabolic enzymes and both show considerable genetic variability between Orientals and Caucasians. There are known marked heterogeneity in susceptibility to various cancers and hypertension among Chinese Mongolian, Hui and Han ethnic
Takako Kawasaki et al.
BMC cancer, 8, 33-33 (2008-01-31)
Cyclooxygenase-2 (COX-2, PTGS2) plays an important role in colorectal carcinogenesis. COX-2 overexpression in colorectal cancer is inversely associated with microsatellite instability (MSI) and the CpG island methylator phenotype (CIMP). Evidence suggests that MSI/CIMP+ colorectal cancer may arise through the serrated
N Singh et al.
JAMA, 283(21), 2822-2825 (2000-06-06)
The effect of calcium carbonate on the absorption of levothyroxine has not been studied systematically. Such a potential drug interaction merits investigation because concurrent treatment with both drugs is common, particularly in postmenopausal women. To investigate the potential interference of
X Pan et al.
Biochemical pharmacology, 48(4), 827-835 (1994-08-17)
The interaction between selective inhibitors of 3',5'-cyclic-nucleotide phosphodiesterase (PDE) III (cyclic GMP inhibited phosphodiesterase) and selective inhibitors of PDE IV (Ro 20-1724 inhibited phosphodiesterase) to attenuate fetal bovine serum-stimulated incorporation of [3H]thymidine into DNA and cell proliferation was studied in
S Häussler et al.
Journal of dairy science (2023-08-29)
The current study was conducted to examine the effect of L-carnitine supplementation on telomere length and mitochondrial DNA copy number (mtDNAcn) per cell in mid-lactation cows challenged by lipopolysaccharide (LPS) in blood and liver. The mRNA abundance of 31 genes
Kyoung-Ho Lee et al.
Mutation research, 540(1), 89-98 (2003-09-16)
Shipbuilding workers are exposed to a variety of genotoxic compounds including polycyclic aromatic hydrocarbons (PAHs). A limited number of studies have been conducted to evaluate biomarkers related to PAH exposure in painters in the shipyard industry. We examined this in
James Chih-Hsin Yang et al.
The Lancet. Oncology, 16(2), 141-151 (2015-01-16)
We aimed to assess the effect of afatinib on overall survival of patients with EGFR mutation-positive lung adenocarcinoma through an analysis of data from two open-label, randomised, phase 3 trials. Previously untreated patients with EGFR mutation-positive stage IIIB or IV
Daniela C Fuhr et al.
The lancet. Psychiatry, 6(2), 115-127 (2019-01-29)
The Thinking Healthy Programme (THP) is a psychological intervention recommended for the treatment of perinatal depression. However, efforts to integrate the intervention at scale into the routines of community health workers who delivered the THP when it was first evaluated
Page 1 of 1
Page 1 of 1