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Nargis Jamila et al.
Journal of enzyme inhibition and medicinal chemistry, 30(1), 133-139 (2014-03-29)
Context: Garcinia hombroniana Pierre, known as manggis hutan in Malaysia is a rich source of xanthones and benzophenones. This study was aimed to isolate and characterize potential cholinesterase inhibitors from the extracts of G. hombroniana bark and investigate their interactions
Yan Han et al.
Chemical & pharmaceutical bulletin, 63(11), 882-889 (2015-11-03)
Novel tranylcypromine/hydroxylcinnamic acid hybrids 15a, b, and 19a-l were designed and synthesized by connecting tranylcypromine with hydroxylcinnamic acid, and their biological activities were evaluated. The in vitro assay of their inhibitory activities against lysine-specific demethylase 1 (LSD1) showed that most
Nguyen-Thach Tung et al.
Archives of pharmacal research, 38(11), 1999-2007 (2015-05-06)
The potential of hydrogel containing nanostructured lipid carriers (NLC) to enhance the skin permeation rate and skin deposition of dexamethasone acetate (DEA) was investigated. The particle size of obtained NLCs was around 224.4 nm. NLCs had core-shell structure and DEA existed
Density, viscosity, and electrolytic conductivity of concentrated aqueous electrolyte solutions at several temperatures. Alkaline-earth chlorides, lanthanum chloride, sodium chloride, sodium nitrate, sodium bromide, potassium nitrate, potassium bromide, and cadmium nitrate.
Isono T.
Journal of Chemical and Engineering Data, 29(1), 45-52 (1984)
Dongzhe Li et al.
Bioresource technology, 200, 579-586 (2015-11-08)
This study investigates alkali-solubilized dissolved organic matter (DOM) and its fate in the anaerobic treatment process. DOM was fractionated into high molecular weight (HMW) protein-like substances (PL), HMW saccharide-like substances (SL), low molecular weight (LMW) PL, LMW SL, and humic
Pei-Ru Wei et al.
International journal of molecular sciences, 16(9), 20943-20968 (2015-09-05)
We designed a study for photodynamic therapy (PDT) using chitosan coated Mg-Al layered double hydroxide (LDH) nanoparticles as the delivery system. A Food and Drug Administration (FDA) approved near-infrared (NIR) fluorescent dye, indocyanine green (ICG) with photoactive properties was intercalated
Fouzi Mouffouk et al.
International journal of nanomedicine, 10, 63-76 (2015-01-08)
Early cancer detection is a major factor in the reduction of mortality and cancer management cost. Here we developed a smart and targeted micelle-based contrast agent for magnetic resonance imaging (MRI), able to turn on its imaging capability in the
Tuomas Mehtiö et al.
Carbohydrate research, 402, 102-110 (2014-12-17)
A series of copolyanhydrides, consisting of 2,3,4,5-tetra-O-acetylgalactaric acid (AGA) and adipic acid (AA) as monomer units, was polymerized. Synthesis of AGA monomer consisted of two steps. First, O-acetylation of galactaric acid secondary hydroxyl groups was performed using acetic anhydride as
Sang Heon Kim et al.
Analytica chimica acta, 1131, 80-89 (2020-09-16)
Sharp-tipped anisotropic silver (Ag) nanostructures are attracting increasing attention because of their unusual optical properties. However, the sharp tips make such nanostructures thermodynamically unstable; thus, they have been considered unsuitable for use in colorimetric sensing because of their tendency to
Juan-Fernando Padín et al.
American journal of physiology. Cell physiology, 305(2), C160-C172 (2013-04-19)
The activity of the plasmalemmal Na(+)/Ca(2+) exchanger (NCX) is highly sensitive to temperature. We took advantage of this fact to explore here the effects of the NCX blocker KB-R7943 (KBR) at 22 and 37°C on the kinetics of Ca(2+) currents
Patrizia Borghetti et al.
Langmuir : the ACS journal of surfaces and colloids, 26(24), 19007-19013 (2010-11-17)
The role of potassium in the formation of synthetic eumelanin aggregates is investigated by atomic force microscopy and soft-X-ray spectroscopy. Control over the thin film granularity is achieved by using K salts, in both drop casting and electrodeposition of eumelanin
Ramakrishna V S Nirogi et al.
Journal of enzyme inhibition and medicinal chemistry, 30(1), 85-97 (2014-03-29)
A series of N'-[3-(indole-1-sulfonyl) aryl]-N,N-dimethyl ethane-1,2-diamines and N'-[3-(indole-1-sulfonyl) aryl]-N,N-dimethyl propane-1,3-diamines was designed and synthesized as 5-HT6 receptor ligands. These compounds, when screened in a functional reporter gene-based assay, displayed potent antagonistic activity with Kb values in the range of 1.8-60 nM.
Johny Nicolas et al.
Environmental science. Processes & impacts, 17(11), 1952-1958 (2015-09-26)
The wide application and production of nanotechnology have increased the interest in studying the toxicity of nano- and micro-sized particles escaping into air from various aspects of the production process. Metal oxides (MOs) are one particular class of particles that
Hariom Gupta et al.
Journal of colloid and interface science, 430, 221-228 (2014-06-24)
Water dispersible and biologically important molecule dehydroascorbic acid (DHA, capable to cross the blood brain barrier) coated Fe3O4 superparamagnetic nanoparticles having an average size of ∼6 nm were synthesized through one pot aqueous coprecipitation method under atmospheric air. An antioxidant
Zhanmin Liu et al.
Carbohydrate polymers, 134, 627-634 (2015-10-03)
Figures of persimmons for the world's top ten persimmon producing countries are about 4000,000 tons in 2011 and are increasing every year according to FAO statistics. However, there is not any report on pectin production by microbial with persimmon peel
Botao Qu et al.
Nanoscale research letters, 10, 42-42 (2015-04-09)
Porous metallic copper was successfully prepared by a simple thermal decomposition strategy. A coordination compound of Cu(BTA)2 with the morphology of micro-rod crystal was synthesized as the precursor. The precursor to copper transformation was performed and annealed at 600°C with
S Sini et al.
Atherosclerosis, 236(1), 162-168 (2014-07-24)
High-density lipoprotein is a heterogeneous class of lipoprotein with diverse antiatherogenic functions. However, these antiatherogenic properties of HDL can be compromised in atherosclerotic conditions. We have recently identified dysfunctionality in HDL even among healthy subjects, during systemic inflammation. This study
Anna Maria Piras et al.
International journal of biological macromolecules, 67, 124-131 (2014-03-26)
A commercially available chitosan (CS) was employed in the formulation of nanoparticles loaded with lysozyme (LZ) as antimicrobial protein drug model. Due to the variability of commercially available batches of chitosans and to the strict dependence of their physical and
Lu Ren et al.
Carbohydrate research, 406, 19-26 (2015-02-07)
A purified water-soluble fraction (ICP5) of a polysaccharide, isolated from a local Maori mushroom Iliodiction cibarium in New Zealand, was investigated for its structural properties. Size exclusion chromatography and dynamic light scattering showed that ICP5 had a large MW of
Donna V Peralta et al.
Journal of microencapsulation, 31(8), 824-831 (2014-08-05)
Progress has been made in using human serum albumin nanoparticles (HSAPs) as promising colloidal carrier systems for early detection and targeted treatment of cancer and other diseases. Despite this success, there is a current lack of multi-functional HSAP hybrids that
Javad Tashkhourian et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 152, 119-125 (2015-07-24)
A rapid, simple and inexpensive spectrofluorimetric sensor for determination of doxycycline based on its interaction with thioglycolic acid-capped cadmium telluride quantum dots (TGA/CdTe QDs) has been developed. Under the optimum experimental conditions, the sensor exhibited a fast response time of
Xiaohu Xia et al.
ACS nano, 9(10), 9994-10004 (2015-09-04)
Peroxidase mimics with dimensions on the nanoscale have received great interest as emerging artificial enzymes for biomedicine and environmental protection. While a variety of peroxidase mimics have been actively developed recently, limited progress has been made toward improving their catalytic
Puja Kumari et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 152, 109-118 (2015-07-22)
This paper reports the enhancement in photoluminescence due to the alkaline ions (M(2+)) co-doping in YVO4:Eu(3+) phosphors prepared by solid state reaction method. The as synthesized samples were found to have single phase tetragonal structure and the incorporation of dopant/codopant
Li-Chai Chen et al.
Molecules (Basel, Switzerland), 20(10), 18551-18564 (2015-10-17)
A new limonoid, swietemacrophin (1), was isolated from the seeds of Swietenia macrophylla, together with five known compounds 2-6. The structure of 1 was determined through extensive 1D/2D-NMR and mass-spectrometric analyses. Swietemacrophin (1), humilinolide F (2), 3,6-O,O-diacetylswietenolide (3), 3-O-tigloylswietenolide (4)
Jingfeng Wang et al.
Bioresource technology, 199, 211-219 (2015-09-01)
The effects of aqueous ammonia pretreatment on structural properties and hydrolysabilities of Chinese Pennisetum and Hybrid Pennisetum were investigated. Aqueous ammonia pretreatment increased cellulose crystallinities and hydrolysabilities of Chinese Pennisetum and Hybrid Pennisetum. Compared with Chinese Pennisetum, Hybrid Pennisetum showed
Farooq A Shah et al.
Infectious disorders drug targets, 15(3), 153-162 (2015-09-04)
Tributylstannic[3-(3,5 -dimethylphenylamido)propionate] is synthesized and characterized by elemental analysis, FT-IR, multinuclear NMR ((1)H, (13)C and (119)Sn) and mass spectrometry. The organic anion was found to act as monodentate O-bound ligand in solution. The compound was screened for the anti-HCV potency
Jun Zhou et al.
Journal of ethnopharmacology, 164, 229-238 (2015-02-24)
Rehmannia glutinosa (Gaertn.) DC. (RG) has been widely used as traditional Chinese herbal medicine for treatment of diabetes and its complications. The polysaccharide fraction of RG has been proposed to possess hypoglycemic effect by intraperitoneal administration, however, the mechanisms responsible
Shuangquan Yao et al.
Bioresource technology, 185, 21-27 (2015-03-10)
To reduce the degradation of cellulose and obtain high molecular weight of hemicellulose from the extracts, pH pre-corrected hot water pretreatment was developed by employing sodium hydroxide (3.9mol/L). The response surface model was established to optimize the extraction process. The
Madhusmita Dhupal et al.
International journal of nanomedicine, 13, 6735-6750 (2018-11-15)
Titanium dioxide nanoparticles (TiO2 NPs) represent a scientific breakthrough in the areas of biological and medicinal applications. Interaction of TiO2 NPs with components of innate immune system remains elusive. This study explored in vitro immunotoxicity of murine macrophage RAW 264.7
Syed Naseer et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 989, 62-70 (2015-03-26)
This article presents the isolation, quantification and antioxidant evaluation of bioactive principles from Epimedium elatum. LC-MS guided isolation technique was applied for the separation of target constituents. Three isolates; magnoflorine, chrysin and dibenzylideneacetone (DBA) were isolated for the first time
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