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Showing 1-30 of 348 results for "419494" within Papers
Weihong Zhao et al.
Clinical and experimental pharmacology & physiology, 42(2), 171-178 (2014-11-18)
Levonorgestrel, a derivative of progesterone, effectively protects women against unwanted pregnancy as an emergency contraceptive. Previous studies have not been successful in determining the mechanism by which levonorgestrel acts. In the present study we analysed cilia beat action and cilia
Emil Paleček et al.
Chemical record (New York, N.Y.), 12(1), 27-45 (2012-01-31)
The ability of proteins to catalyze hydrogen evolution has been known for more than 80 years, but the poorly developed d.c. polarographic "pre-sodium wave" was of little analytical use. Recently, we have shown that by using constant current chronopotentiometric stripping
Ying Dong et al.
Fish & shellfish immunology, 97, 375-381 (2019-12-25)
Infectious pancreatic necrosis virus (IPNV) is a common pathogen that causes huge economic losses for the salmonid aquaculture industry. Autophagy plays an important regulatory role in the invasion of pathogenic microorganisms. In this study, we explored the relationship between IPNV
Sibel Türedi et al.
Electromagnetic biology and medicine, 34(4), 390-397 (2014-08-29)
The growing spread of mobile phone use is raising concerns about the effect on human health of the electromagnetic field (EMF) these devices emit. The purpose of this study was to investigate the effects on rat pup heart tissue of
Hariom Gupta et al.
Journal of colloid and interface science, 430, 221-228 (2014-06-24)
Water dispersible and biologically important molecule dehydroascorbic acid (DHA, capable to cross the blood brain barrier) coated Fe3O4 superparamagnetic nanoparticles having an average size of ∼6 nm were synthesized through one pot aqueous coprecipitation method under atmospheric air. An antioxidant
Soumalya Mukherjee et al.
Ecotoxicology and environmental safety, 113, 112-123 (2014-12-17)
The natural habitat of sponge, Eunapius carteri faces an ecotoxicological threat of contamination by washing soda, a common household cleaning agent of India. Washing soda is chemically known as sodium carbonate and is reported to be toxic to aquatic organisms.
Irina Drachuk et al.
ACS nano, 9(2), 1219-1235 (2015-01-15)
This study introduces double-brush designs of functionalized silk polyelectrolytes based upon regenerated silk fibroin (SF), which is modified with poly-L-lysine (SF-PLL), poly-L-glutamic acid (SF-PGA), and poly(ethylene glycol) (PEG) side chains with different grafting architecture and variable amino acid-PEG graft composition
Jimmi Cording et al.
Antioxidants & redox signaling, 23(13), 1035-1049 (2015-04-29)
Tight junctions (TJs) seal paracellular clefts in epithelia/endothelia and form tissue barriers for proper organ function. TJ-associated marvel proteins (TAMPs; tricellulin, occludin, marvelD3) are thought to be relevant to regulation. Under normal conditions, tricellulin tightens tricellular junctions against macromolecules. Traces
Lei Wang et al.
PloS one, 10(2), e0118134-e0118134 (2015-02-18)
Diabetic peripheral neuropathy is a common complication of long-standing diabetes mellitus. To mimic clinical trials in which patients with diabetes enrolled have advanced peripheral neuropathy, we investigated the effect of sildenafil, a specific inhibitor of phosphodiesterase type 5 enzyme, on
Longhai Qiu et al.
Annals of biomedical engineering, 43(12), 2924-2940 (2015-05-28)
Our group pioneered the study of nerve regeneration in China and has successfully developed human "acellular nerve grafts (ACNGs)". However, our clinical studies revealed that the effects of ACNGs for long and large nerve defects are far from satisfactory. To
O N Ponamoreva et al.
Biosensors & bioelectronics, 67, 321-326 (2014-09-10)
The methylotrophic Pichia angusta VKM Y-2559 and the oleaginous Cryptococcus curvatus VKM Y-3288 yeast cells were immobilized in a bimodal silica-organic sol-gel matrix comprised of tetraethoxysilane (TEOS), the hydrophobic additive methyltriethoxysilane (MTES) and the porogen polyethylene glycol (PEG). Under carefully
Xiaoyan Bai et al.
American journal of nephrology, 40(6), 523-534 (2015-01-13)
Vascular endothelial growth factor-A (VEGF-A) upregulation and podocyte apoptosis have been documented in diabetes. This study was designed to investigate whether inhibiting VEGF-A could ameliorate podocyte apoptosis in diabetes and the underlying mechanisms. In vitro, small interfering RNAs (siRNAs) of
Courtney Reichhardt et al.
Biochimica et biophysica acta, 1848(1 Pt B), 378-383 (2014-06-10)
Bacterial biofilms are communities of bacterial cells surrounded by a self-secreted extracellular matrix. Biofilm formation by Vibrio cholerae, the human pathogen responsible for cholera, contributes to its environmental survival and infectivity. Important genetic and molecular requirements have been identified for
Song-Fa Zhang et al.
Autophagy, 11(2), 225-238 (2015-01-22)
Paclitaxel is recommended as a first-line chemotherapeutic agent against ovarian cancer, but drug resistance becomes a major limitation of its success clinically. The key molecule or mechanism associated with paclitaxel resistance in ovarian cancer still remains unclear. Here, we showed
Ang Tian et al.
International journal of nanomedicine, 10, 2423-2439 (2015-04-08)
Cells respond to their surroundings through an interactive adhesion process that has direct effects on cell proliferation and migration. This research was designed to investigate the effects of TiO2 nanotubes with different topographies and structures on the biological behavior of
Pamela Ruiz et al.
Marine environmental research, 111, 107-120 (2015-08-25)
The aim of this work was to study short-term effects on antioxidant enzyme activities and long-term genotoxic and carcinogenic potential of CuO nanoparticles (NPs) in comparison to bulk CuO and ionic copper in mussels Mytilus galloprovincialis after 21 days exposure
Alessandra M Cathel et al.
The European journal of neuroscience, 40(8), 3202-3214 (2014-08-19)
Endocannabinoids acting at the cannabinoid type 1 receptor (CB1R) are known to regulate attention, cognition and mood. Previous studies have shown that, in the rat medial prefrontal cortex (mPFC), CB1R agonists increase norepinephrine release, an effect that may be attributed
Zhaowei Zhu et al.
Cellular and molecular neurobiology, 35(2), 273-282 (2014-10-17)
This study aimed to investigate whether or not ginkgo biloba extract (EGb 761) enhances peripheral nerve regeneration and vascularization after repair using acellular nerve allografts (ANA). Seventy-two Sprague-Dawley rats were randomly divided into three experimental groups: a unilateral 15-mm sciatic
Doory Kim et al.
PloS one, 10(4), e0124581-e0124581 (2015-04-16)
Correlative fluorescence light microscopy and electron microscopy allows the imaging of spatial distributions of specific biomolecules in the context of cellular ultrastructure. Recent development of super-resolution fluorescence microscopy allows the location of molecules to be determined with nanometer-scale spatial resolution.
Vacuum ultraviolet spectra of osmium tetroxide and ruthenium tetroxide.
Roebber JL, et al.
J. Chem. Phys. , 60(8), 3166-3173 (1974)
Jong Hye Cheong et al.
Biological & pharmaceutical bulletin, 38(1), 102-108 (2015-03-07)
Autophagy has been an emerging field in the treatment of hepatic carcinoma since anticancer therapies were shown to ignite autophagy in vitro and in vivo. Here we report that ginsenoside Rg3 and Rh2, major components of red ginseng, induce apoptotic
Kate P M Ricketts et al.
Small (Weinheim an der Bergstrasse, Germany), 10(19), 3954-3961 (2014-07-06)
In order to maximize the potential of nanoparticles (NPs) in cancer imaging and therapy, their mechanisms of interaction with host tissue need to be fully understood. NP uptake is known to be dramatically influenced by the tumor microenvironment, and an
Fabio Andrés Persia et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(11), 1400-1405 (2014-07-11)
The aim of this study was to determine whether hydroxytyrosol and oleuropein, the major phenols found in olives and olive oil, inhibit mast cell activation induced by immune and non-immune pathways. Purified peritoneal mast cells were preincubated in the presence
Fakhroddin Mesbah et al.
Journal of ovarian research, 8, 74-74 (2015-11-19)
Metformin decreases polycystic ovary syndrome (PCOS) symptoms, induces ovulation, and may improve developmental competence of in vitro oocyte maturation. This study was designed to define the effects of metformin on the characteristics of in vitro oocyte maturation in estradiol valerate
Seishiro Hirano et al.
PloS one, 10(11), e0142062-e0142062 (2015-11-07)
The Macrophage Receptor with COllagenous structure (MARCO) protein is a plasma membrane receptor for un-opsonized or environmental particles on phagocytic cells. Here, we show that MARCO was internalized either by ruffling of plasma membrane followed by macropinocytosis or by endocytosis
Rachel Parke-Houben et al.
Journal of materials science. Materials in medicine, 26(2), 107-107 (2015-02-11)
Three-dimensional scaffolds based on inverted colloidal crystals (ICCs) were fabricated from sequentially polymerized interpenetrating polymer network (IPN) hydrogels of poly(ethyleneglycol) and poly(acrylic acid). This high-strength, high-water-content IPN hydrogel may be suitable for use in an artificial cornea application. Development of
Judit M Veres et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(49), 16194-16206 (2014-12-05)
Axo-axonic cells (AACs) in cortical regions selectively innervate the axon initial segments (AISs) of principal cells (PCs), where the action potentials are generated. These GABAergic interneurons can alter the activity of PCs, but how the efficacy of spike control correlates
Marc A Beckerman et al.
Experimental neurology, 239, 120-132 (2012-10-16)
Corticotropin-releasing factor (CRF) and glutamate are critical signaling molecules in the central nucleus of the amygdala (CeA). Central amygdala CRF, acting via the CRF type 1 receptor (CRF-R1), plays an integral role in stress responses and emotional learning, processes that
Tevfik Ziypak et al.
Renal failure, 37(2), 343-354 (2014-12-20)
To determine the protective effect of aliskiren on ischemia-reperfusion (I/R) injury in a rat renal (I/R) model. Rats were randomly divided into five groups: sham control group; sham control with aliskiren pretreatment; I/R group and I/R with two doses of
Cornelia Neidlinger-Wilke et al.
Spine, 39(17), 1355-1364 (2014-05-17)
Conditioned media (CM) of cartilaginous endplates (CEPs) of intervertebral discs were analyzed in a bioassay with regard to their influence on matrix turnover and inflammatory factors on nucleus pulposus (NP) cells of the same patient. CEP tissue underwent further histological
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