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Mark G Jones et al.
Clinica chimica acta; international journal of clinical chemistry, 361(1-2), 150-158 (2005-07-05)
Previous work by others have suggested the occurrence of one or more chemical or metabolic 'markers' for ME/CFS including specific amino acids and organic acids and a number of unidentified compounds (CFSUM1, CFSUM2). We have shown elsewhere that CFSUM1 is
Thanh Ha Nguyen et al.
The journal of physical chemistry. A, 116(23), 5618-5628 (2012-05-03)
The experimental charge density distributions in a host-guest complex have been determined. The host, 1,4-bis[[(6-methylpyrid-2-yl)amino]carbonyl]benzene (1) and guest, adipic acid (2). The molecular geometries of 1 and 2 are controlled by the presence in the complex of intermolecular hydrogen bonding
Adipic aciduria, a dietary artefact.
N Glick et al.
Journal of inherited metabolic disease, 14(5), 849-850 (1991-01-01)
Totan Adak et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 47(3), 217-225 (2012-03-02)
Amphiphilic copolymers, synthesized from poly (ethylene glycols) and various aliphatic diacids, which self assemble into nano-micellar aggregates in aqueous media, were used to develop controlled release (CR) formulations of imidacloprid [1-(6 chloro-3-pyridinyl methyl)-N-nitro imidazolidin-2-ylideneamine] using encapsulation technique. High solubilisation power
Ketonic decarboxylation catalysed by weak bases and its application to an optically pure substrate
Renz M and Corma A
European Journal of Organic Chemistry, 2004(9), 2036-2039 (2004)
Krzysztof J Paluch et al.
Journal of pharmaceutical sciences, 100(8), 3268-3283 (2011-04-08)
The production of salt or cocrystalline forms is a common approach to alter the physicochemical properties of pharmaceutical compounds. The goal of this work was to evaluate the impact of anion choice (succinate, adipate, and sulfate) on the physicochemical characteristics
Guang Hong et al.
Dental materials journal, 31(1), 139-149 (2012-01-27)
The purpose of this study was to investigate the use of different plasticizers in soft acrylic resin materials to reduce leaching of the plasticizer and thus increase the durability of tissue conditioners. Samples were prepared containing different combinations of three
Zachary J Reitman et al.
Nature chemical biology, 8(11), 887-889 (2012-09-25)
Mutations in an enzyme can result in a neomorphic catalytic activity in cancers. We applied cancer-associated mutations from isocitrate dehydrogenases to homologous residues in the active sites of homoisocitrate dehydrogenases to derive enzymes that catalyze the conversion of 2-oxoadipate to
Ju-Hyun Park et al.
International journal of toxicology, 30(6), 700-706 (2011-10-14)
The present study was carried out to investigate the oral single and repeat toxicity of cross-linked β-cyclodextrin (β-CD) made with adipic acid. Ten each of female and male rats were orally administered a 5000 mg/kg single dose. At this dose
A biocatalyst inspired by cancer.
Lenny Dang
Nature chemical biology, 8(11), 874-875 (2012-10-19)
G Hoffmann et al.
Clinical chemistry, 35(4), 587-595 (1989-04-01)
This new method for qualitative and quantitative determination of organic acids, aldehydes, and ketones in biological samples is effective for use with urine, plasma, and amniotic fluid, and it requires no deproteinization. Isolation by batch-wise liquid partition chromatography on silicic
H Vierhapper et al.
Acta endocrinologica, 122(6), 753-758 (1990-06-01)
In patients with anorexia nervosa 24-h mean plasma concentration of cortisol were 0.44 +/- 0.09 mumol/l (normal less than 0.28 mumol/l). Following stimulation by ACTH (1-24) urinary excretion rates of cortisol were stimulated from 0.22 +/- 0.08 to 4.85 +/-
Yan-Hung Chen et al.
Applied biochemistry and biotechnology, 166(7), 1711-1722 (2012-02-14)
The aim of this investigation was to synthesize the adipic acid-modified magnetic nanoparticles for the efficient immobilization of C-terminally lysine-tagged α-amylase (BACΔNC-Lys₇) from thermophilic Bacillus sp. strain TS-23. The carboxylated magnetic nanoparticles were prepared by the simple co-precipitation of Fe³⁺/Fe²⁺
M M Coude et al.
Journal of inherited metabolic disease, 14(5), 668-673 (1991-01-01)
Organic acids have been determined in aqueous humour and plasma by gas chromatography-mass spectrometry in 38 cases of infant death and 4 cases of inherited metabolic disease: one had a complex fatty-acid oxidation disorder with a large urinary excretion of
Zafar A Siddiqi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 93, 280-289 (2012-04-10)
The present ternary complexes [Cu(ada)(phen)(H(2)O)]·2H(2)O (1), [Co(2)(ada)(2)(phen)(2)(H(2)O)(2)] (2) and [{Cu(ada)(3)(bipy)}(n)·3nH(2)O] (3) (H(2)ada=adipic acid, phen=1,10-phenanthroline and bipy=2,2'-bipyridine) obtained under varying experimental conditions were characterized by spectral, electrochemical and thermal studies. The bonding modes and the spatial arrangements of the carboxylate dianion
C D Capo-Chichi et al.
The American journal of clinical nutrition, 71(4), 978-986 (2000-03-25)
Riboflavin, flavin mononucleotide (FMN), and flavin adenine dinucleotide (FAD) concentrations have been little studied in cases of malnutrition. Our objective was to investigate the effects of malnutrition on riboflavin status and riboflavin's relation with thyroid hormones and concentrations of urinary
Huijuan Wei et al.
ACS applied materials & interfaces, 4(8), 4106-4112 (2012-07-11)
The oxidation-resistant acidic resins are of great importance for the catalytic oxidation systems. In this paper, the oxidatively stable acidic resins are obtained from the cation ion exchange resins (CIERs) through the thermal treatment in N(2) atmosphere. The structure and
C D Capo-chichi et al.
The American journal of clinical nutrition, 69(4), 672-678 (1999-04-10)
Thyroid hormones, riboflavin, riboflavin cofactors, and organic acids were assessed in girls with anorexia nervosa. The objective was to examine the effect of malnutrition and low thyroid hormone concentrations on erythrocyte and plasma riboflavin metabolism and their relation with urinary
F Guneral et al.
Clinical chemistry, 40(6), 862-866 (1994-06-01)
Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days to 16 years, subdivided into five age groups. We quantified 69
Mohamad F Aslam et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(8), 3671-3678 (2014-04-30)
The ferritin core is composed of fine nanoparticulate Fe(3+) oxohydroxide, and we have developed a synthetic mimetic, nanoparticulate Fe(3+) polyoxohydroxide (nanoFe(3+)). The aim of this study was to determine how dietary iron derived in this fashion is absorbed in the
C Romero et al.
Poultry science, 91(5), 1149-1157 (2012-04-14)
Effects of dietary adipic acid (0 vs. 1%) and corn dried distillers grains with solubles (DDGS; 0 vs. 20%) were evaluated on hen performance and egg characteristics from 26 to 34 wk of age. Four isocaloric and isonitrogenous diets were
M A Shirai et al.
Carbohydrate polymers, 92(1), 19-22 (2012-12-12)
Biodegradable films were produced from blends contained a high amount of thermoplastic starch (TPS) and poly(lactic acid) (PLA) plasticized with different adipate or citrate esters. It was not possible to obtain pellets for the production of films using only glycerol
Gregory Kaler et al.
The Journal of biological chemistry, 282(33), 23841-23853 (2007-06-08)
Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding preferences and transport function of
J D Shoemaker et al.
Journal of chromatography, 562(1-2), 125-138 (1991-01-02)
Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease, followed by azeotropic dehydration. The "Target Analyte Search" program provided with the VG Trio
Trevor W Stone et al.
European journal of pharmacology, 650(2-3), 568-578 (2010-11-06)
The simple diamine diaminoethane (ethylenediamine, EDA) has been shown to activate GABA receptors in the central and peripheral nervous systems, partly by a direct action and partly by releasing endogenous GABA. These effects have been shown to be produced by
Marta Worzakowska
Molecules (Basel, Switzerland), 20(6), 10594-10603 (2015-06-11)
Cinnamyl long chain aroma esters were prepared by using the conventional and microwave-assisted methods. The esterification reaction of naturally occurring 3-phenyl-prop-2-en-1-ol and different chain lengths acidic and diol reagents was carried out at the temperature of 140 °C under solvent
Tânia Veiga et al.
Metabolic engineering, 14(4), 437-448 (2012-04-25)
Industrial production of semi-synthetic cephalosporins by Penicillium chrysogenum requires supplementation of the growth media with the side-chain precursor adipic acid. In glucose-limited chemostat cultures of P. chrysogenum, up to 88% of the consumed adipic acid was not recovered in cephalosporin-related
Hans F N Kvitvang et al.
Analytical chemistry, 83(7), 2705-2711 (2011-03-11)
Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few internal standards representing all metabolites, the ultimate requirement for a quantitative description of
J E Pettersen
Clinica chimica acta; international journal of clinical chemistry, 58(1), 43-50 (1975-01-06)
1. Using the combined gas-liquid chromatography-mass spectrometry technique it was shown that ketotic patients excreted up to 273 mg of hexanedioic acid daily in their urine, whereas serum samples from these patients contained only trace amounts of this acid. Healthy
Tuomas Mehtiö et al.
Carbohydrate research, 402, 102-110 (2014-12-17)
A series of copolyanhydrides, consisting of 2,3,4,5-tetra-O-acetylgalactaric acid (AGA) and adipic acid (AA) as monomer units, was polymerized. Synthesis of AGA monomer consisted of two steps. First, O-acetylation of galactaric acid secondary hydroxyl groups was performed using acetic anhydride as
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