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Alessia Salzillo et al.
International journal of molecular sciences, 22(16) (2021-08-28)
Despite the recurring outbreak of resistance mechanisms and adverse reactions, doxorubicin (Doxo) still remains the standard-of-care for several cancers, including osteosarcoma (OS). As an appealing source of phytochemical compounds, naturally occurring molecules have extensively been reported to overcome Doxo limitations
Yong Fan et al.
Journal of pharmaceutical and biomedical analysis, 95, 213-219 (2014-04-02)
Sample extraction is the first challenge in analysis of herbal medicines (HMs). Numerous methods have been developed to improve extraction efficiency, use less solvent and short time. In this work, a tissue-smashing based ultra-rapid extraction (TSURE) method has been proposed
What is green coffee extract?
Wendy Marcason
Journal of the Academy of Nutrition and Dietetics, 113(2), 364-364 (2013-01-29)
Francesco Menichini et al.
Journal of enzyme inhibition and medicinal chemistry, 29(5), 677-685 (2013-10-10)
Cardiospermum halicacabum is widely used in traditional medicine. Previous studies have focused on the aerial parts, while the seeds have been poorly investigated. This work aimed to analyse the chemical composition of extracts from aerial parts and seeds obtained using
Juan Kang et al.
Biochimica et biophysica acta, 1674(2), 205-214 (2004-09-18)
The interactions of chlorogenic acid and ferulic acid with human serum albumin (HSA) have been investigated by fluorescence and Fourier transformed infrared (FT-IR) spectrometry. Fluorescence results showed that one molecule of protein combined with one molecule of drugs at the
Muhammad Mir Showkat et al.
Molecules (Basel, Switzerland), 24(18) (2019-09-13)
Phenolic acids including chlorogenic acids are major polyphenolic compounds found in Jerusalem artichoke (Helianthus tuberosus L.). The plant itself is an emerging biorefinery crop due to the inulin-rich tubers, a bioethanol feedstock, but the aerial parts represent a rich source
Rui-Song Huang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(5), 762-767 (2013-06-04)
To establish quality standard of Zhuang medicine Lonicera dasystyla, and provide scientific basis for the quality control of L. dasystyla. Characteristics of materia medica, microscopic features, TLC indentification, inspection, extractum and determination of chlorogenic acid, macranthoidin B, dipsacoside B were
Naiani Ferreira Marques et al.
Neurochemical research, 40(6), 1197-1210 (2015-04-24)
Oxidative stress has been implicated in several pathologies including neurological disorders. Centella asiatica is a popular medicinal plant which has long been used to treat neurological disturbances in Ayurvedic medicine. In the present study, we quantified of compounds by high
Reuven Rasooly et al.
Journal of food science, 75(5), M296-M301 (2010-07-16)
In the present study, we evaluated Shiga toxin (Stx2) activity in apple juices by measuring a decrease in dehydrogenase activity of Vero cells with the microculture tetrazolium (MTT) assay. Freshly prepared juice from Red Delicious apples and Golden Delicious apples
Usune Etxeberria et al.
Natural product communications, 10(8), 1417-1420 (2015-10-06)
The use of biocompounds as agents with potential anti-obesity effects might be a feasible alternative to the prescription of traditional drugs in the near future. The goal of the present study was to screen five different compounds in relation to
Sinéad Currivan et al.
Journal of chromatography. A, 1402, 82-93 (2015-05-30)
Zwitterionic methacrylate based polymeric monolithic columns were prepared in two-step polymerizations, with reduced polymerization times. Characteristic properties such as hydrodynamic permeability, porosity, retention factors, and pore size distribution charts were used for column evaluation. A scaffold column was fabricated by
Semih Otles et al.
TheScientificWorldJournal, 2012, 564367-564367 (2012-05-18)
Types of nettles (Urtica dioica) were collected from different regions to analyze phenolic compounds in this research. Nettles are specially grown in the coastal part. According to this kind of properties, nettle samples were collected from coastal part of (Mediterranean
Yonghui Li et al.
The American journal of Chinese medicine, 41(1), 221-229 (2013-01-23)
In this paper, a useful method for screening and analyzing the potential bioactive components from Reduning Injection was developed using macrophage cell extraction and ultra-high performance liquid chromatography coupled with Q-TOF/MS spectrometry. In addition, the protective effects on macrophage cell
Li-Min Liu et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 70, 179-184 (2014-05-23)
Chinese herbal medicinal plants, Euonymus laxiflorus (EL), Rubia lanceolata (RL) and Gardenia jasminoides (GJ), have been used wildly to treat arthritis and gout in Taiwan for decades. To understand the beneficial effects of these three plants, their xanthine oxidase (XO)
Wieland Peschel et al.
Talanta, 140, 150-165 (2015-06-07)
The medicinal use of different chemovars and extracts of Cannabis sativa L. requires standardization beyond ∆9-tetrahydrocannabinol (THC) with complementing methods. We investigated the suitability of (1)H NMR key signals for distinction of four chemotypes measured in deuterated dimethylsulfoxide together with
Yuji Matsui et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 858(1-2), 96-105 (2007-09-04)
A method using liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) was developed for the simultaneous analysis of nine chlorogenic acids (CGAs), three isomers each of caffeoylquinic acids (CQAs), feruloylquinic acids (FQAs) and dicaffeoylquinic acids (dCQAs), and their two metabolites, caffeic acid
Hsin-Lun Huang et al.
Journal of medicinal food, 18(6), 663-676 (2015-02-05)
Intestinal microflora and inflammation are associated with the risk of inflammatory bowel diseases. Noni (Morinda citrifolia L.) has various bioactivities, but its effect on colon health remains unknown. This study focused on the effects of fermented noni fruit extracts on
Zhi-Ping Xue et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(21), 3179-3181 (2013-02-13)
To study the content change of chlorogenic acid in honeysuckle under different temperature, and predict its term of validity at room temperature. The content of chlorogenic acid was assayed by HPLC. The activation energy E(a) and the decomposition rate constant
R Ejzemberg et al.
Anais da Academia Brasileira de Ciencias, 71(2), 273-277 (1999-07-21)
Previous research on plants used in folk medicine as antidotes against snake-bite revealed some constituents responsible for such protection. Chlorogenic acid (3-0-caffeoyl quinic acid) was one of these substances, studied with more attention. It has been shown that this substance
Agnieszka Bazylko et al.
Journal of photochemistry and photobiology. B, Biology, 149, 189-195 (2015-06-21)
Galinsoga species are used in folk medicine as anti-inflammatory agents and accelerators for wound healing. They also have reported antioxidant activity. We examined aqueous and ethanolic extracts derived from the Galinsoga herb as potential photoprotectors, as the role of reactive
Yanchun Zhong et al.
Current pharmaceutical biotechnology, 21(11), 1099-1106 (2020-03-20)
Chlorogenic Acid (CA) has diverse, recognized health effects. This study aimed to explore the effects of CA on fat reduction and the underlying mechanism of these effects. First, we established a Monosodium Glutamate (MSG)-induced obesity mouse model and subjected the
Akinobu Tanaka et al.
Molecules (Basel, Switzerland), 19(6), 8238-8260 (2014-06-20)
Besides being a useful building material, bamboo also is a potential source of bioactive substances. Although some studies have been performed to examine its use in terms of the biological activity, only certain parts of bamboo, especially the leaves or
Pei-Rong Lin et al.
Journal of ethnopharmacology, 262, 113190-113190 (2020-07-31)
Kucha tea plant (Camellia assamica var. kucha Chang et Wang) is regarded as a mutant variety of wild Pu'er tea plant found in few mountain areas of Yunnan, China. Its fresh young leaves and shoots are picked by the indigenous
Yoshiko Hada et al.
International journal of molecular sciences, 21(12) (2020-07-08)
The world faces the serious problem of aging. In this study, we aimed to investigate the effect of chlorogenic acid (CGA) on vascular senescence. C57/BL6 female mice that were 14 ± 3 months old were infused with either Angiotensin II
Alexandra Epure et al.
Plants (Basel, Switzerland), 10(1) (2021-01-06)
The present study analyzed the methanol extract and tincture obtained from the spontaneous Romanian Cichorium intybus species, in order to evaluate polyphenols content and some biological properties. Chromatographic and spectrophotometric methods were used for the analysis of polyphenols and the
Inês M Valente et al.
Food research international (Ottawa, Ont.), 116, 888-896 (2019-02-06)
For the first time, seven European varieties of Vicia faba L. seeds were investigated for (1) their phytonutrients profile by HPLC-DAD-MS/MS, (2) total phenolic content (TPC), and (3) antioxidant capacity (DPPH and FRAP assays). A wide range of compounds were
Jin Mi Chun et al.
BMC complementary and alternative medicine, 14, 234-234 (2014-07-12)
Houttuynia cordata Thunb. (Saururaceae) has been used in traditional medicine for treatment of inflammatory diseases. This study evaluated the anti-inflammatory effects of an ethyl acetate fraction derived from a Houttuynia cordata extract (HCE-EA) on the production of inflammatory mediators and
Ying Liu et al.
Food chemistry, 185, 159-164 (2015-05-09)
In this study, polyphenols from lotus seed epicarp (PLSE) at three different ripening stages were purified by column chromatography and identified by RP-HPLC and HPLC-ESI-MS(2). The antioxidant activities of PLSE were also investigated. We found that the contents of PLSE
Chao-Mei Ma et al.
Bioorganic & medicinal chemistry, 18(19), 7009-7014 (2010-09-04)
New derivatives of caffeic acid and quinic acid were synthesized and their anti-fungal and inhibitory activities on fungal 1,3-β-glucan synthase were determined in comparison with those of the corresponding chlorogenic acid derivatives. All the chlorogenic, quinic and caffeic acid derivatives
Mariam Jarouche et al.
Plants (Basel, Switzerland), 8(12) (2019-12-19)
Lycium (also known as Goji berry) is used in traditional Chinese medicine (TCM) with claimed benefits, including eye and liver protection, immune system fortification and blood glucose control. The commercially available product comes from either the L.barbarum or L.chinense species
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