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Syaghalirwa N M Mandiki et al.
Steroids, 70(2), 85-94 (2005-01-06)
Sex steroid inhibitors were used to characterize the effects of 17beta-estradiol (E2) and testosterone (T) on the sexual growth dimorphism of Eurasian perch juveniles. In experiment 1, growth responses to different doses of either E2 (25, 50, 75, and 100...
J T Eppig et al.
Genetics, 103(4), 797-812 (1983-04-01)
Murine ovarian teratomas were used to determine recombination percentages for gene-gene and centromere-gene intervals. Data were obtained utilizing a recombinant inbred strain, LTXBJ, and a number of newly developed LT/SvEi congenic strains.--Centromere-gene recombination was measured at 11.3 +/- 1.2% for...
F Moreno et al.
European journal of biochemistry, 161(3), 565-569 (1986-12-15)
Hexokinase PII is not inhibited by high Mg-ATP concentrations if the Mg2+-free ATP is kept at low levels (0.01 mM) in the assay mixture. Hexokinase PI activity is not affected either by Mg2+-free ATP nor by free Mg2+ in the...
Ruilong Liu et al.
Nature communications, 10(1), 991-991 (2019-03-03)
6-Phosphogluconate dehydrogenase (6PGD) is a key enzyme that converts 6-phosphogluconate into ribulose-5-phosphate with NADP+ as cofactor in the pentose phosphate pathway (PPP). 6PGD is commonly upregulated and plays important roles in many human cancers, while the mechanism underlying such roles...
David J Waxman et al.
Methods in molecular biology (Clifton, N.J.), 320, 91-96 (2006-05-25)
A spectrofluorometric method is described for the determination of CYP2A6-catalyzed coumarin 7-hydroxylation. Following acidification of the reaction mixture, the enzymatic product, 7-hydroxycoumarin, is recovered by a double-extraction procedure and assayed using an excitation wavelength of 370 nm and an emission...
Ana C A X De-Oliveira et al.
PloS one, 10(1), e0117842-e0117842 (2015-01-31)
Mouse cytochrome P450 (CYP) 2A5 is induced by inflammatory conditions and infectious diseases that down-regulate the expression and activity of most other CYP isoforms. Enhanced oxidative stress and nuclear factor (erythroid 2-related factor) 2 (Nrf2) transcription factor activation have been...
Petra Bonova et al.
Journal of neurochemistry, 154(1), 99-111 (2019-10-11)
The indirect use of the protective potential of stem cells in the form of cell secretomes has become an attractive strategy in regenerative medicine. In the present work, we studied the paracrine activity of blood cells that could be modulated...
J T Yang et al.
The Journal of cell biology, 135(3), 829-835 (1996-11-01)
It has been suggested, on the basis of immunolocalization studies in vivo and antibody blocking experiments in vitro, that alpha 4 integrins interacting with vascular cell adhesion molecule 1 (VCAM-1) are involved in myogenesis and skeletal muscle development. To test...
Considine, DM et al.
Van Nostrand Reinhold Encyclopedia of Chemistry, 1993-1993 null
K E Olagaray et al.
PloS one, 14(1), e0210744-e0210744 (2019-01-24)
Systemic inflammation is common in early lactation dairy cows and is associated with decreased milk production. The Scutellaria baicalensis plant contains flavonoids with anti-inflammatory and anti-oxidative properties, which may counteract the inflammatory state in early lactation dairy cows. The objective...
Darren M Gordon et al.
Archives of biochemistry and biophysics, 672, 108072-108072 (2019-08-20)
Obesity is the predominant cause of non-alcoholic fatty liver disease (NAFLD), which is associated with insulin resistance and diabetes. NAFLD includes a spectrum of pathologies that starts with simple steatosis, which can progress to non-alcoholic steatohepatitis (NASH) with the commission...
Tanya Fradin et al.
Journal of leukocyte biology, 104(5), 1023-1039 (2018-07-17)
A central event in the activation of the phagocyte NADPH oxidase involves binding of p67phox to the dehydrogenase region of Nox2. The identity of the binding site in Nox2 is unknown. By measuring binding of p67phox to synthetic Nox2 peptides...
Marcel A Vieira-Lara et al.
BMC biology, 19(1), 154-154 (2021-08-01)
The skeletal muscle plays a central role in glucose homeostasis through the uptake of glucose from the extracellular medium in response to insulin. A number of factors are known to disrupt the normal response to insulin leading to the emergence...
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