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RAB0476

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Association between TNF alpha-308 G/A polymorphism and oral lichen planus (OLP): a meta-analysis
Zhou Yand Vieira AR
Journal of Applied Oral Science : Revista FOB, 26 (2018)
Yaoxian Liang et al.
Biological & pharmaceutical bulletin, 37(10), 1599-1605 (2014-08-05)
Renal ischemia-reperfusion (I/R) injury is a major cause of acute kidney injury via inflammation and cell apoptosis. Volatile anesthetics have been shown to exert organ-protective effects against kidney damage in vivo and in vitro. In the present study, we investigated
Yuri L Boteon et al.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 25(7), 1007-1022 (2019-03-02)
Strategies to increase the use of steatotic donor livers are required to tackle the mortality on the transplant waiting list. We aimed to test the efficacy of pharmacological enhancement of the lipid metabolism of human livers during ex situ normothermic
Jae-Ho Choi et al.
Journal of medicinal food, 17(10), 1113-1121 (2014-09-18)
Sasang constitutional medicine is a major branch of Korean traditional oriental medicine. Constitutions of Sasang medicine are classified into Taeyangin, Taeumin, Soyangin, and Soumin. We investigated immunostimulatory activities of fermented soybean product (FSP) extracts and their major bioactive compounds, isoflavone
Qian-Li Ma et al.
Biomaterials, 35(37), 9853-9867 (2014-09-10)
The use of endosseous implanted materials is often limited by undesirable effects that may be due to macrophage-related inflammation. The purpose of this study was to fabricate a nanostructured surface on a titanium implant to regulate the macrophage inflammatory response
Chul Won Lee et al.
Journal of ethnopharmacology, 155(2), 1141-1155 (2014-07-01)
Clematis mandshurica Ruprecht root is widely used in Asia as an analgesic and anti-inflammatory agent. This research investigated the anti-inflammatory effects of Clematis mandshurica Ruprecht root extract (CRE) using RAW 264.7 macrophage cells and carrageenan- (CA-) induced rat paw edema.
Min Jiang et al.
PloS one, 9(5), e96214-e96214 (2014-05-09)
Flos Lonicerae Japonicae (FLJ) is an important cash crop in eastern Asia, and it is an anti-inflammatory Traditional Chinese Medicine. There are large variations in the quality of the marketed FLJ products. To find marker ingredients useful for quality control
Raffaele Altara et al.
BMC biotechnology, 14, 63-63 (2014-07-16)
Inflammatory mediators can serve as biomarkers for the monitoring of the disease progression or prognosis in many conditions. In the present study we introduce an adaptation of a membrane-based technique in which the level of up to 40 cytokines and
Bao-Sheng Zhao et al.
Molecules (Basel, Switzerland), 19(10), 16925-16936 (2014-10-24)
As one of the most important components of Panax ginseng, ginsenoside Rg1 has certain anti-aging effects, improving the activity of learning and memory. Studies have showed that ginsenoside Rg1 improves the memory impairment associated with Alzheimer's disease (AD). In this
Carol Arely Botello Amaro et al.
Molecules (Basel, Switzerland), 19(8), 11366-11384 (2014-08-05)
The metabolic syndrome (MS) is a condition consisting of various metabolic abnormalities that are risk factors for developing kidney failure, cardiovascular, vascular and cerebrovascular diseases, among others. The prevalence of this syndrome shows a marked increase. The aim of this
Ali M El-Halawany et al.
Scientific reports, 4, 5880-5880 (2014-08-01)
Aframomum melegueta is a commonly used African spice. Through a hepatoprotective bioassay-guided isolation, the chloroform fraction of A.melegueta seeds yielded one new diarylheptanoid named 3-(S)-acetyl-1-(4'-hydroxy-3', 5'-di methoxyphenyl)-7-(3″,4″, 5″-trihydroxyphenyl)heptane (1), and two new hydroxyphenylalkanones, [8]-dehydrogingerdione (2) and [6]-dehydroparadol (3), in addition
S Saravanan et al.
Inflammation, 37(5), 1374-1388 (2014-04-17)
Swertiamarin is a secoiridoid glycoside found in Enicostema axillare (Lam) A. Raynal, a medicinal plant used as a depurative in the Indian system of traditional medicine. The present study evaluated the immunomodulatory activity of isolated swertiamarin. In vivo immunomodulatory activity
Guillermo Marcial et al.
Journal of ethnopharmacology, 155(2), 1125-1133 (2014-07-06)
The aerial parts of Lippia integrifolia (Gris.) Hieronymus (Verbenaceae), known as incayuyo, are used by the peasant population of Argentina for treatment of diseases related to a gastrointestinal system, mainly for inflammation of the stomach and have also been included
Mousa O Germoush et al.
Journal of cancer research and clinical oncology, 140(7), 1103-1109 (2014-04-20)
The present study was designed to investigate the possible protective effects of berberine against cyclophosphamide (CP)-induced hepatotoxicity in rats. The experimental rats were treated with berberine orally at a dose of 50 mg/kg for 11 consecutive days after the administration
Association of HLA?DRB1* 13 and TNF?α gene polymorphisms with clearance of chronic hepatitis B infection and risk of hepatocellular carcinoma in Thai population.
Kummee P, et al.
Journal of Viral Hepatitis, 14(12), 841-848 (2007)
Yuan Gao et al.
PloS one, 9(5), e96741-e96741 (2014-05-08)
Genkwanin is one of the major non-glycosylated flavonoids in many herbs with anti-inflammatory activities. Although its anti-inflammatory activity in vivo has been reported, the potential molecular mechanisms remain obscure. In this study, by pharmacological and genetic approaches, we explore the
M Pesce et al.
Brain, behavior, and immunity, 41, 251-260 (2014-05-06)
Recent lines of research have boosted awareness of the immunological facets of schizophrenia. However, associations with protein tyrosine phosphatase regulators have never been reported. The aim of our study was to investigate the expression and promoter status methylation of phosphatase
Tanshinone II is a potent candidate for treatment of lipopolysaccharide-induced acute lung injury in rat model
Li L, et al.
Oncology Letters, 15(2), 2550-2554 (2018)
Reem N El-Naga et al.
Neurotoxicology, 44, 48-57 (2014-06-01)
The relationship between inflammation, oxidative stress and the incidence of depression had been well studied. Indole-3-carbinol (I3C), a natural active compound found in cruciferous vegetables, was shown to have anti-oxidant and anti-inflammatory activities. Therefore, the aim of this study was
Aurigena Antunes de Araújo et al.
PloS one, 9(5), e96750-e96750 (2014-05-14)
The aim of this study was to evaluate the effects of azilsartan (AZT) on bone loss, inflammation, and the expression of matrix metallo proteinases (MMPs), receptor activator of nuclear factor κB ligand (RANKL), receptor activator of nuclear factor κB (RANK)
Esteban Grasso et al.
PloS one, 9(5), e97147-e97147 (2014-05-23)
Macrophages at the maternal-placental interface coordinate opposite demands under the control of trophoblast cells such as the response against pathogens on one hand, and apoptotic cell clearance and wound healing with the production of suppressor cytokines. Here, we investigated whether
T Jakobsson et al.
Mucosal immunology, 7(6), 1416-1428 (2014-05-08)
We examined the function of the oxysterol receptors (LXRs) in inflammatory bowel disease (IBD) through studying dextran sodium sulfate (DSS)- and 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in mice and by elucidating molecular mechanisms underlying their anti-inflammatory action. We observed that
H Özyurt et al.
Free radical research, 48(10), 1247-1255 (2014-07-22)
Ionizing radiation (IR) can induce cell damage and cell death through the reactive oxygen species generated by radiolytic hydrolysis. The present study was aimed to determine the possible protective effects of quercetin, a well-known antioxidant agent, against IR-induced bladder and
Hsiu-Yun Lai et al.
Maturitas, 79(3), 329-333 (2014-08-19)
To determine whether higher serum levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and high sensitivity C-reactive protein (CRP) were associated with frailty in the older institutionalized men. The study enrolled 386 residents from a veterans care home in northern
Xiaohui Wang et al.
Cardiovascular research, 102(3), 385-395 (2014-03-01)
The present study examined the role of microRNA-125b (miR-125b) in myocardial ischaemia/reperfusion (I/R) injury. We constructed lentivirus-expressing miR-125b (LmiR-125b) and developed transgenic mice with overexpression of miR-125b. LmiR-125b was transfected into mouse hearts through the right common carotid artery. Lentivirus
Lihong Fan et al.
Cellular and molecular neurobiology, 34(7), 999-1010 (2014-06-18)
This study evaluated whether bone marrow-derived mesenchymal stem cells (BM-MSCs) combined with xenogeneic acellular nerve grafts (xANGs) would reduce the inflammation reaction of xANGs transplantation. BM-MSCs were extracted, separated, purified, and cultured from the bone marrow of rats. Then BM-MSCs
Jianmin Chen et al.
PloS one, 9(6), e100631-e100631 (2014-06-20)
Development of cardiac dysfunction is associated with increased morbidity and mortality in patients with sepsis. Increasing evidence shows that gender determines the degree of inflammatory response of the host and that females tolerate sepsis better than males. It is unknown
Yue Hou et al.
Progress in neuro-psychopharmacology & biological psychiatry, 54, 92-102 (2014-04-09)
The present study aims to evaluate the effects of pterostilbene on lipopolysaccharide (LPS)-induced learning and memory impairment as well as the possible changes of microglia and neurons. Firstly, learning and memory function was investigated by behavioral tests. Pterostilbene attenuated LPS-induced
Ismail M Meraz et al.
PloS one, 9(4), e94703-e94703 (2014-04-17)
Porous silicon (pSi) microparticles, in diverse sizes and shapes, can be functionalized to present pathogen-associated molecular patterns that activate dendritic cells. Intraperitoneal injection of MPL-adsorbed pSi microparticles, in contrast to free MPL, resulted in the induction of local inflammation, reflected
Wei-wei Zhou et al.
Free radical biology & medicine, 74, 50-63 (2014-06-25)
Alzheimer disease (AD) is characterized by extracellular senile plaques, intracellular neurofibrillary tangles, and memory loss. Aggregated amyloid-β (Aβ), oxidative stress, and inflammation have pivotal roles in the pathogenesis of AD. Therefore, the inhibition of Aβ-induced neurotoxicity, oxidative stress, and inflammation
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