Synthesis and biological evaluation of dehydroabietic acid derivatives.

European journal of medicinal chemistry (2009-11-07)
Miguel A González, David Pérez-Guaita, Julieth Correa-Royero, Bibiana Zapata, Lee Agudelo, Ana Mesa-Arango, Liliana Betancur-Galvis
ABSTRACT

A series of C18-oxygenated derivatives of dehydroabietic acid were synthesized from commercial abietic acid and evaluated for their cytotoxic, antimycotic, and antiviral activities.

MATERIALS
Product Number
Brand
Product Description

Supelco
Abietic acid, technical, ~75% (GC)
Sigma-Aldrich
Dehydroabietic acid, ≥95% (LC/MS-ELSD)