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Merck

CCL2

chemokine (C-C motif) ligand 2

Synonymes:
GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6347) Summary: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008]
  • Mouse(20296) chemokine (C-C motif) ligand 2
  • Rat(24770) chemokine (C-C motif) ligand 2
  • dog(403981) chemokine (C-C motif) ligand 2
  • naked mole-rat(101697988) chemokine (C-C motif) ligand 2
  • Domestic Rabbit(100009130) chemokine (C-C motif) ligand 2
  • domestic guinea pig(100135494) chemokine (C-C motif) ligand 2
  • Horse(100034136) chemokine (C-C motif) ligand 2
  • cow(281043) chemokine (C-C motif) ligand 2
  • sheep(101120093) chemokine (C-C motif) ligand 2
  • sheep(100294591) chemokine (C-C motif) ligand 2

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Mouse MCP-1 / CCL2 ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse
Rat MCP-1 / CCL2 ELISA Kit, for cell and tissue lysates,
Espèce(s)
rat
Rat MCP-1 / CCL2 ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
rat
Mouse MCP-1 / CCL2 ELISA Kit, for cell and tissue lysates,
Espèce(s)
mouse
Canine CCL2 / C-C Motif Chemokine 2 ELISA Kit, ,
Espèce(s)
dog

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Monoclonal Anti-Monocyte Chemotactic Protein-1 antibody produced in mouse, clone 24822, purified immunoglobulin, lyophilized powder,
Espèces réactives
human
Application
neutralization
western blot
Human MCP-1 Conferma® ELISA, quantification of human MCP-1 in serum, plasma, or culture media samples.,
Espèces réactives
human
Application
ELISA
Anticorps anti-CCL2, clone 2D8, clone 2D8, from mouse,
Espèces réactives
human, monkey, mouse, rat
Application
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-CCL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-MCP-1 Antibody, clone 2G17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
affinity binding assay
immunofluorescence

immunohistochemistry

western blot

Proteins

Numéro du produit
Description
Espèce(s)
MCP-1/MCAF human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
human
Monocyte Chemotactic Protein-1 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Espèce(s)
human
Monocyte Chemotactic Protein-1, Recombinant rat, The Macrophage/monocyte chemoattractant protein-1 (or MCP-1 protein) plays an important role in the inflammatory response of blood monocytes & tissue macrophages.,
Espèce(s)
rat
JE/MCP-1 (CCL2) from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
mouse
SILuLite CCL2 C-C motif chemokine 2 human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CCL2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Ccl2,
Espèce(s)
mouse