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Merck

PAK2

p21 protein (Cdc42/Rac)-activated kinase 2

Synonymes:
PAK65, PAKgamma
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(5062) Summary: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
  • Mouse(224105) p21 protein (Cdc42/Rac)-activated kinase 2
  • Rat(29432) p21 protein (Cdc42/Rac)-activated kinase 2
  • domestic guinea pig(100713135) p21 protein (Cdc42/Rac)-activated kinase 2
  • naked mole-rat(101710712) p21 protein (Cdc42/Rac)-activated kinase 2
  • chicken(424860) p21 protein (Cdc42/Rac)-activated kinase 2
  • sheep(101123517) p21 protein (Cdc42/Rac)-activated kinase 2
  • Domestic Rabbit(100009535) p21 protein (Cdc42/Rac)-activated kinase 2
  • dog(612814) p21 protein (Cdc42/Rac)-activated kinase 2
  • domestic cat(101082845) p21 protein (Cdc42/Rac)-activated kinase 2
  • cow(513673) p21 protein (Cdc42/Rac)-activated kinase 2

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-phospho-PAK2 (pSer141) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
Anti-PAK2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-PAK2 antibody produced in mouse, clone 1E1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
proximity ligation assay

western blot
Anti-Phospho-PAK2-S20 antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
western blot
Anti-phospho-PAK1/PAK2/PAK3 (pThr423/pThr402/pThr421) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

Proteins

Numéro du produit
Description
Espèce(s)
PAK2, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PAK2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Pak2,
Espèce(s)
mouse