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Merck

PRMT6

protein arginine methyltransferase 6

Synonymes:
HRMT1L6
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(55170) Summary: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
  • Mouse(99890) protein arginine N-methyltransferase 6
  • Rat(295384) protein arginine methyltransferase 6
  • domestic cat(101093626) protein arginine methyltransferase 6
  • domestic guinea pig(100725259) protein arginine methyltransferase 6
  • cow(540228) protein arginine methyltransferase 6
  • Thale Cress(821541) protein arginine N-methyltransferase 6
  • naked mole-rat(101715374) protein arginine methyltransferase 6
  • sheep(101119859) protein arginine methyltransferase 6
  • Zebrafish(448867) protein arginine methyltransferase 6
  • dog(490133) protein arginine methyltransferase 6

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-PRMT6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-PRMT6 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, rat
Application
ChIP
western blot
Anti- PRMT6 antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-PRMT6 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, pig, rat
Application
ELISA
western blot
Anti-PRMT6 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
bovine, dog, guinea pig, horse, human, rat
Application
western blot

Proteins

Numéro du produit
Description
Espèce(s)
PRMT6 active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Espèce(s)
human
PRMT6 human, recombinant, expressed in FreeStyle 293-F cells, ≥70% (SDS-PAGE),
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human PRMT6,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Prmt6,
Espèce(s)
mouse