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Merck

SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Synonymes:
ASV, SRC1, c-SRC, p60-Src
Espèce(s):
Human SRC (6714), Mouse Src (20779), Rat Src (83805), Zebrafish src (325084), chicken SRC (396442), domestic cat SRC (101100378), dog SRC (485864), sheep SRC (101103084), cow SRC (535742), domestic guinea pig Src (100728509)
ID UniProtKB:
P12931, E1P5V4, Q76P87, Q86VB9, Q9H5A8
ID du gène:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

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Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
695017
Acide phosphorique, ACS reagent, ≥85 wt. % in H2O,
Espèce(s)
human
438081
Acide phosphorique, ACS reagent, ≥85 wt. % in H2O,
Espèce(s)
human
27109
Acide citrique, meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance),
Espèce(s)
human
345245
Acide phosphorique, 85 wt. % in H2O, 99.99% trace metals basis,
Espèce(s)
human
251275
Acide citrique, ACS reagent, ≥99.5%,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
SAB6012515
KD-Validated Anti-phospho-Src (Tyr419) Antibody, clone 23GB4080, Rabbit Monoclonal, clone 23GB4080, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
flow cytometry
western blot
SAB6012526
KD-Validated Anti-phospho-Src (Tyr529) Antibody, clone 23GB6690, Rabbit Monoclonal, clone 23GB6690, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
western blot
SAB6012539
KD-Validated Anti Src Antibody, clone 23GB1110, Rabbit Monoclonal, clone 23GB1110, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
flow cytometry
immunofluorescence
western blot
SAB6012540
KD-Validated Anti Src Antibody, clone 23GB985, Rabbit Monoclonal, clone 23GB985, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
flow cytometry
immunofluorescence
western blot
SAB6012542
KD-Validated Anti Src Antibody, clone 23GB980, Rabbit Monoclonal, clone 23GB980, recombinant rabbit monoclonal, expressed in HEK293 cells,
Espèces réactives
human, rat
Application
flow cytometry
immunofluorescence
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
S9692
SU 6656, ≥98% (HPLC),
Espèce(s)
human
R2146
Radicicol from Diheterospora chlamydosporia, solid,
Espèce(s)
human, rat
E2250
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Espèce(s)
human, rat
T182
Tyrphostin A9, solid,
Espèce(s)
mouse, human
SML2589
Dasatinib, ≥98% (HPLC),
Espèce(s)
human

Kits

Numéro du produit
Description
Espèce(s)
20-121
Src Kinase Reaction Buffer, ,
Espèce(s)
human

Proteins

Numéro du produit
Description
Espèce(s)
S1076
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
14-326-M
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Espèce(s)
human
14-746-M
Src (1-530) Protein, active, 10 µg, ,
Espèce(s)
human
14-748-M
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Espèce(s)
human
S5564
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
EMU071351
MISSION® esiRNA, targeting mouse Src,
Espèce(s)
mouse

Small Molecule - Substrate

Numéro du produit
Description
Espèce(s)
12-140
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Espèce(s)
human