ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
Sinonimi:
ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1
Specie:
Human ABCA4 (24), Mouse Abca4 (11304), Rat Abca4 (310836), chicken ABCA4 (424490), Horse ABCA4 (100058746), dog ABCA4 (444852), domestic cat ABCA4 (101099571), Thale Cress ABCA4 (823929), naked mole-rat Abca4 (101725111), domestic guinea pig Abca4 (100725431) ...Più
ID UniProtKB:
ID gene:
- Human(24) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Jul 2008]
- Mouse(11304) ATP-binding cassette, sub-family A (ABC1), member 4
- Rat(310836) ATP-binding cassette, subfamily A (ABC1), member 4
- chicken(424490) ATP-binding cassette, sub-family A (ABC1), member 4
- Horse(100058746) ATP-binding cassette, sub-family A (ABC1), member 4
- dog(444852) ATP-binding cassette, sub-family A (ABC1), member 4
- domestic cat(101099571) ATP-binding cassette, sub-family A (ABC1), member 4
- Thale Cress(823929) ATP binding cassette subfamily A4
- naked mole-rat(101725111) ATP-binding cassette, sub-family A (ABC1), member 4
- domestic guinea pig(100725431) ATP-binding cassette, sub-family A (ABC1), member 4
- sheep(101107561) ATP-binding cassette, sub-family A (ABC1), member 4
- cow(281584) ATP-binding cassette, sub-family A (ABC1), member 4
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-ABCA4 Antibody, clone 5B4, clone 5B4, from mouse,
Reattività con
bovine, human, mouse
Applicazione
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-ABCA4 Antibody, clone 3F4, clone 3F4, from mouse,
Reattività con
bovine, human
Applicazione
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-ABCA4 Antibody, clone 5D7.1, clone 5D7.1, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Anti-ABCA4 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
Anti-ABCA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Numero di prodotto
Descrizione
Specie