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Merck

ACE

angiotensin I converting enzyme

Sinonimi:
ACE1, CD143, DCP, DCP1, ICH, MVCD3
Specie:
ID UniProtKB:
ID gene:
  • Human(1636) Summary: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
  • Mouse(11421) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Rat(24310) angiotensin I converting enzyme
  • fruit fly(41625) Acetylcholine esterase
  • Zebrafish(565980) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • chicken(419953) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • dog(610668) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Horse(100064801) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • cow(509484) angiotensin I converting enzyme
  • sheep(554335) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Domestic Rabbit(100009274) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Mouse ACE  ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
mouse
Human ACE ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-ACE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-ACE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Monoclonal Anti-CD143 antibody produced in mouse, clone 5-369,
Reattività con
human
Applicazione
flow cytometry
Anti-ACE1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
western blot
Anti-Angiotensin Converting Enzyme Antibody, clone 2E2, culture supernatant, clone 2E2, from mouse,
Reattività con
human, rat
Applicazione
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
6-Mercaptohexanoic acid, 90%,
Specie
rat
Ramipril, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Lisinopril, ≥98% (HPLC),
Specie
human
Lisinopril, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Ramipril, ≥98% (HPLC),
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
Angiotensin Converting Enzyme from porcine kidney, lyophilized powder, ≥10 units/mg protein (Bradford),
Specie

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human ACE, CTD-2501B8.1,
Specie
human

Small Molecule - Substrate

Numero di prodotto
Descrizione
Specie
N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC),
Specie
mouse, human, rat
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly, ,
Specie
mouse, human, rat
Hippuryl-His-Leu acetate salt, ,
Specie
mouse, human, rat