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Merck

ACVR2A

activin A receptor, type IIA

Sinonimi:
ACTRII, ACVR2
Specie:
ID UniProtKB:
ID gene:
  • Human(92) Summary: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
  • Mouse(11480) activin receptor IIA
  • Rat(29263) activin A receptor, type IIA
  • cow(281598) activin A receptor, type IIA
  • Horse(100049823) activin A receptor, type IIA
  • sheep(443304) activin A receptor, type IIA
  • dog(476140) activin A receptor, type IIA
  • naked mole-rat(101707586) activin A receptor, type IIA
  • domestic guinea pig(100731791) activin A receptor, type IIA
  • chicken(396324) activin A receptor, type IIA
  • domestic cat(101097750) activin A receptor, type IIA

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human Activin R2A ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-ACVR2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human ACVR2A,
Specie
human
MISSION® esiRNA, targeting mouse Acvr2a,
Specie
mouse