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Merck

ANK2

ankyrin 2, neuronal

Sinonimi:
ANK-2, LQT4, brank-2
Specie:
ID UniProtKB:
ID gene:
  • Human(287) Summary: This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]
  • Mouse(109676) ankyrin 2, brain
  • Rat(362036) ankyrin 2, neuronal
  • naked mole-rat(101697466) ankyrin 2, neuronal
  • domestic guinea pig(100717265) ankyrin 2, neuronal
  • sheep(101115623) ankyrin 2, neuronal
  • chicken(422689) ankyrin 2, neuronal
  • domestic cat(101100129) ankyrin 2, neuronal
  • dog(487908) ankyrin 2, neuronal
  • fruit fly(38863) Ankyrin 2
  • Horse(100064198) ankyrin 2, neuronal

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-ANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-ANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Monoclonal Anti-Ankyrin B - Atto 390 antibody produced in mouse, clone S105-13, purified immunoglobulin,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Ankyrin B - Rpe antibody produced in mouse, clone S105-13, purified immunoglobulin,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Ankyrin B - Atto 594 antibody produced in mouse, clone S105-13, purified immunoglobulin,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ank2,
Specie
mouse
MISSION® esiRNA, targeting human ANK2,
Specie
human