Passa al contenuto
Merck

AOC2

amine oxidase, copper containing 2 (retina-specific)

Sinonimi:
DAO2, RAO
Specie:
ID UniProtKB:
ID gene:
  • Human(314) Summary: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(237940) amine oxidase, copper containing 2 (retina-specific)
  • Domestic Rabbit(100353051) amine oxidase, copper containing 2 (retina-specific)
  • domestic cat(101080592) amine oxidase, copper containing 2 (retina-specific)
  • dog(490957) amine oxidase, copper containing 2 (retina-specific)
  • sheep(101106783) amine oxidase, copper containing 2 (retina-specific)
  • Thale Cress(822168) allene oxide cyclase 2
  • cow(100336082) amine oxidase, copper containing 2 (retina-specific)

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-AOC2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, horse, human, mouse, rabbit
Applicazione
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human AOC2,
Specie
human
MISSION® esiRNA, targeting mouse Aoc2,
Specie
mouse