AR
androgen receptor
Sinonimi:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Specie:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), fruit fly ar (44503), Zebrafish ar (100005148), chicken AR (422165), dog AR (403588), domestic cat AR (101081787), domestic cat AR (751827), Horse AR (100033980) ...Più
ID UniProtKB:
ID gene:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- fruit fly(44503) abdomen rotatum
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- dog(403588) androgen receptor
- domestic cat(101081787) androgen receptor
- domestic cat(751827) androgen receptor
- Horse(100033980) androgen receptor
- cow(280675) androgen receptor
- sheep(443042) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- domestic guinea pig(100726891) androgen receptor
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Small Molecule - Activator
Numero di prodotto
Descrizione
Specie
Small Molecule - Agonist
Numero di prodotto
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Specie
Testosterone solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Methandienone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Small Molecule - Antagonist
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP242, affinity isolated antibody,
Reattività con
dog, human, mouse, pig, rabbit, rat
Applicazione
immunohistochemistry
Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal, culture supernatant, Upstate®,
Reattività con
human
Applicazione
western blot
Anti-Androgen Receptor antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP107, affinity isolated antibody,
Reattività con
dog, human, mouse, pig, rat
Applicazione
immunohistochemistry
Anti-AR (n-terminal) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM254, purified immunoglobulin,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Monoclonal Anti-AR antibody produced in mouse, clone 1G3, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
proximity ligation assay
western blot
immunohistochemistry
proximity ligation assay
western blot
Small Molecule - Blocker
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Specie
Small Molecule - Inhibitor
Small Molecule - Ligand
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Descrizione
Specie