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Merck

BAD

BCL2-associated agonist of cell death

Sinonimi:
BBC2, BCL2L8
Specie:
ID UniProtKB:
ID gene:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
2,3-Dihydroxynaphthalene, ≥98.0% (HPLC),
Specie
human
4-Biphenylacetic acid, 98%,
Specie
human
Biphenyl-4-carboxylic acid, 95%,
Specie
human
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-BAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-phospho BAD Antibody (Ser155), from rabbit, purified by affinity chromatography,
Reattività con
bovine, canine, human, mouse, rat
Applicazione
immunoprecipitation (IP)
inhibition assay

western blot
Anti-Phospho-Bad (Ser99) Antibody, from rabbit,
Reattività con
human
Applicazione
western blot
Anti-Phospho-Bad-S112 antibody produced in rabbit, ,
Reattività con
human
Applicazione
western blot
Anti-Phospho- Bad (Ser75) Antibody, from rabbit,
Reattività con
human, mouse, rat
Applicazione
western blot

Proteins

Numero di prodotto
Descrizione
Specie
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human BAD,
Specie
human