CBFB
core-binding factor, beta subunit
Sinonimi:
PEBP2B
Specie:
Human CBFB (865), Mouse Cbfb (12400), Rat Cbfb (361391), dog CBFB (479690), domestic guinea pig Cbfb (100733237), naked mole-rat Cbfb (101723908), cow CBFB (614678), sheep CBFB (101106455), domestic cat CBFB (101087541), Zebrafish cbfb (30744)
ID UniProtKB:
ID gene:
- Human(865) Summary: The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)]
- Mouse(12400) core binding factor beta
- Rat(361391) core-binding factor, beta subunit
- dog(479690) core-binding factor, beta subunit
- domestic guinea pig(100733237) core-binding factor, beta subunit
- naked mole-rat(101723908) core-binding factor, beta subunit
- cow(614678) core-binding factor, beta subunit
- sheep(101106455) core-binding factor, beta subunit
- domestic cat(101087541) core-binding factor, beta subunit
- Zebrafish(30744) core-binding factor, beta subunit
- chicken(395257) core-binding factor, beta subunit
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CBFB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
KD-Validated Anti Core-binding factor subunit beta Antibody, clone 23GB3785, Rabbit Monoclonal, clone 23GB3785, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
western blot
western blot
esiRNA
Numero di prodotto
Descrizione
Specie