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Merck

CCR8

chemokine (C-C motif) receptor 8

Sinonimi:
CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1
Specie:
ID UniProtKB:
ID gene:
  • Human(1237) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
  • Mouse(12776) chemokine (C-C motif) receptor 8
  • Rat(301066) chemokine (C-C motif) receptor 8
  • domestic guinea pig(100725278) chemokine (C-C motif) receptor 8
  • naked mole-rat(101706054) chemokine (C-C motif) receptor 8
  • domestic cat(101099650) chemokine (C-C motif) receptor 8
  • cow(407772) chemokine (C-C motif) receptor 8
  • sheep(101113281) chemokine (C-C motif) receptor 8
  • dog(485600) chemokine (C-C motif) receptor 8
  • chicken(420718) chemokine (C-C motif) receptor 8

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CCR8 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry
Anti-CCR8 antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
human
Applicazione
western blot
Anti-CCR8 Antibody, clone C8Mab-2, ,
Reattività con
mouse
Applicazione
flow cytometry
immunocytochemistry

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CCR8,
Specie
human
MISSION® esiRNA, targeting mouse Ccr8,
Specie
mouse