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Merck

CD74

CD74 molecule, major histocompatibility complex, class II invariant chain

Sinonimi:
DHLAG, HLADG, II, Ia-GAMMA
Specie:
Human CD74 (972), Mouse Cd74 (16149), Rat Cd74 (25599), cow CD74 (613384), domestic cat CD74 (101085953), domestic guinea pig Cd74 (100735496), dog CD74 (479329), sheep CD74 (101102561), chicken CD74 (414741), naked mole-rat Cd74 (101723625)
ID UniProtKB:
P04233, A8K7R1, B4DNE8, D3DQG3, D3DQG4, Q14597, Q29832, Q5U0J8
ID gene:
  • Human(972) Summary: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  • Mouse(16149) CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • Rat(25599) Cd74 molecule, major histocompatibility complex, class II invariant chain
  • cow(613384) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic cat(101085953) CD74 molecule, major histocompatibility complex, class II invariant chain
  • domestic guinea pig(100735496) CD74 molecule, major histocompatibility complex, class II invariant chain
  • dog(479329) CD74 molecule, major histocompatibility complex, class II invariant chain
  • sheep(101102561) CD74 molecule, major histocompatibility complex, class II invariant chain
  • chicken(414741) CD74 molecule, major histocompatibility complex, class II invariant chain
  • naked mole-rat(101723625) CD74 molecule, major histocompatibility complex, class II invariant chain

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ELISA

Numero di prodotto
Descrizione
Specie
RAB1351
Human CD74 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
HPA010592
Anti-CD74 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
MABF33
Anticorpo anti-MHC di classe II (I-A/I-E), clone M5/114, clone M5/114, from rat,
Reattività con
mouse
Applicazione
flow cytometry
immunohistochemistry
western blot
MABF141C
Anti-MHC class II (I-A/I-E), redFluor® 710, clone M5/114 .15.2 Antibody, clone M5/114.15.2, from rat, redFluor® 710,
Reattività con
mouse
Applicazione
flow cytometry
MABF141B
Anti-MHC class II (I-A/I-E), violetFluor® 450, clone M5/114 .15.2 Antibody, clone M5/114.15.2, from rat, violetFluor® 450,
Reattività con
mouse
Applicazione
flow cytometry
SAB5201950
Monoclonal Anti-CD74 antibody produced in mouse, clone 3D7,
Reattività con
human
Applicazione
flow cytometry
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
EMU077571
MISSION® esiRNA, targeting mouse Cd74,
Specie
mouse
EHU157961
MISSION® esiRNA, targeting human CD74,
Specie
human