CDC27
cell division cycle 27
Sinonimi:
ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
Specie:
Human CDC27 (996), Mouse Cdc27 (217232), Rat Cdc27 (360643), naked mole-rat Cdc27 (101717421), domestic cat CDC27 (101091234), fruit fly Cdc27 (38798), dog CDC27 (490924), chicken CDC27 (419960), cow CDC27 (540660), domestic guinea pig Cdc27 (100731091) ...Più
ID UniProtKB:
ID gene:
- Human(996) Summary: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(217232) cell division cycle 27
- Rat(360643) cell division cycle 27
- naked mole-rat(101717421) cell division cycle 27
- domestic cat(101091234) cell division cycle 27 homolog (S. cerevisiae)
- fruit fly(38798) CG8610 gene product from transcript CG8610-RB
- dog(490924) cell division cycle 27 homolog (S. cerevisiae)
- chicken(419960) cell division cycle 27 homolog (S. cerevisiae)
- cow(540660) cell division cycle 27 homolog (S. cerevisiae)
- domestic guinea pig(100731091) cell division cycle 27
- Zebrafish(30450) cell division cycle 27
- Horse(100054552) cell division cycle 27 homolog (S. cerevisiae)
- sheep(101121276) cell division cycle 27 homolog (S. cerevisiae)
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Cdc27 antibody,Mouse monoclonal, clone AF3.1, purified from hybridoma cell culture,
Reattività con
xenopus, bovine, canine, human, mouse, rat
Applicazione
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot