CDK2
cyclin-dependent kinase 2
Sinonimi:
p33(CDK2)
Specie:
Human CDK2 (1017), Mouse Cdk2 (12566), Rat Cdk2 (362817), domestic guinea pig Cdk2 (100714324), Zebrafish cdk2 (406715), chicken CDK2 (100529062), naked mole-rat Cdk2 (101725353), dog CDK2 (606931), domestic cat CDK2 (101093368), sheep CDK2 (100216433) ...Più
ID UniProtKB:
ID gene:
- Human(1017) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
- Mouse(12566) cyclin-dependent kinase 2
- Rat(362817) cyclin dependent kinase 2
- domestic guinea pig(100714324) cyclin-dependent kinase 2
- Zebrafish(406715) cyclin-dependent kinase 2
- chicken(100529062) cyclin-dependent kinase 2
- naked mole-rat(101725353) cyclin-dependent kinase 2
- dog(606931) cyclin-dependent kinase 2
- domestic cat(101093368) cyclin-dependent kinase 2
- sheep(100216433) cyclin-dependent kinase 2
- Domestic Rabbit(100134865) cyclin-dependent kinase 2
- cow(519217) cyclin-dependent kinase 2
- Goat(100860751) cyclin-dependent kinase 2
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-phospho-CDK2 (pThr160) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-CDK2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7990, purified immunoglobulin, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Cdk2 Antibody, clone AN4.3, clone AN4.3, Upstate®, from mouse,
Reattività con
xenopus, human, mouse
Applicazione
immunoprecipitation (IP)
western blot
western blot
Anti-phospho-CDK1/CDC2 (pThr14) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-phospho-CDK1/CDC2 (pThr14) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Proteins
Numero di prodotto
Descrizione
Specie
p27 Protein complex, activated, 10 µg, Activated complex of three (3) full length, recombinant human proteins: p27, Cyclin E1, & CDK2. Phosphorylated in vitro using CDK2/Cyclin E1. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.,
Specie
human
Cdk1/cyclin B Protein, active, 10 µg, Active, C-terminal His6-tagged human full length Cdk1 & N-terminal GST-tagged human full length Cyclin B, for use in Kinase Assays.,
Specie
human
Cdk2/Cyclin E Protein, active, 10 µg, Active complex of recombinant full length human Cdk2 containing a C-terminal His6-tag & recombinant full-length human Cyclin E containing an N-terminal GST-tag. For use in Kinase Assays.,
Specie
human
CDK2/CyclinA1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human