CRYBA1
crystallin, beta A1
Sinonimi:
CRYB1, CTRCT10
Specie:
Human CRYBA1 (1411), Mouse Cryba1 (12957), Rat Cryba1 (25583), domestic guinea pig Cryba1 (100379565), naked mole-rat Cryba1 (101696796), dog CRYBA1 (491178), cow CRYBA1 (282202), sheep CRYBA1 (101109193), chicken CRYBA1 (396499), domestic cat CRYBA1 (101093724)
ID UniProtKB:
ID gene:
- Human(1411) Summary: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. [provided by RefSeq, Jul 2008]
- Mouse(12957) crystallin, beta A1
- Rat(25583) crystallin, beta A1
- domestic guinea pig(100379565) crystallin, beta A1
- naked mole-rat(101696796) crystallin, beta A1
- dog(491178) crystallin, beta A1
- cow(282202) crystallin, beta A1
- sheep(101109193) crystallin, beta A1
- chicken(396499) crystallin, beta A1
- domestic cat(101093724) crystallin, beta A1
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CRYBA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
esiRNA
Numero di prodotto
Descrizione
Specie