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Merck

CTSL

cathepsin L

Sinonimi:
CATL, CTSL1, MEP
Specie:
Human CTSL (1514), Mouse Ctsl (13039)
ID UniProtKB:
ID gene:
  • Human(1514) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(13039) cathepsin L

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ELISA

Numero di prodotto
Descrizione
Specie
RAB0635
Human CTSL / Cathepsin L1 ELISA Kit, ,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
HPA070413
Anti-CTSL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
western blot
SAB4300959
Anti-CTSL antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
C2970
Monoclonal Anti-Cathepsin L antibody produced in mouse, clone 33/2, ascites fluid,
Reattività con
human, mink, mouse, rat
Applicazione
ELISA
immunohistochemistry
microarray
western blot

Proteins

Numero di prodotto
Descrizione
Specie
219402
Cathepsin L, Human Liver, Cathepsin L, Human Liver, CAS 60616-82-2, is a native, the most potent of all the lysosomal proteinases. Plays a major role in the proteolysis of both cellular and endocytosed macromolecules.,
Specie
human
SRP0291
Cathepsin L Active human, recombinant, expressed in FreeStyle™ 293-F cells, ≥90% (SDS-PAGE),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU106791
MISSION® esiRNA, targeting human CTSL,
Specie
human