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Merck

CYBB

cytochrome b-245, beta polypeptide

Sinonimi:
AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Specie:
Human CYBB (1536), Mouse Cybb (13058), Rat Cybb (66021), cow CYBB (281112), sheep CYBB (100036757), Domestic Rabbit CYBB (100008801), dog CYBB (491825), chicken CYBB (418581), Zebrafish cybb (393386)
ID UniProtKB:
P04839, A8K138, Q2PP16
ID gene:
  • Human(1536) Summary: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Mouse(13058) cytochrome b-245, beta polypeptide
  • Rat(66021) cytochrome b-245, beta polypeptide
  • cow(281112) cytochrome b-245, beta polypeptide
  • sheep(100036757) cytochrome b-245, beta polypeptide
  • Domestic Rabbit(100008801) cytochrome b-245 beta polypeptide
  • dog(491825) cytochrome b-245, beta polypeptide (chronic granulomatous disease)
  • chicken(418581) cytochrome b-245, beta polypeptide
  • Zebrafish(393386) cytochrome b-245, beta polypeptide (chronic granulomatous disease)

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
ZRB2447
Anti-NOX2/gp91phox Antibody, clone 1J16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
MABS2195
Anti-gp91phox (NOX2) Antibody, ,
Reattività con
human
Applicazione
flow cytometry
western blot
07-024
Anti-gp91-phox Antibody, Upstate®, from rabbit,
Reattività con
human
Applicazione
western blot
MABS2193
Anti-gp91phox (NOX2) Antibody, ,
Reattività con
human
Applicazione
flow cytometry
inhibition assay
western blot
SAB4300724
Anti-CYBB antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
EHU010941
MISSION® esiRNA, targeting human CYBB,
Specie
human