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Merck

CYP2E1

cytochrome P450, family 2, subfamily E, polypeptide 1

Sinonimi:
CPE1, CYP2E, P450-J, P450C2E
Specie:
ID UniProtKB:
ID gene:
  • Human(1571) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008]
  • Mouse(13106) cytochrome P450, family 2, subfamily e, polypeptide 1
  • Rat(25086) cytochrome P450, family 2, subfamily e, polypeptide 1
  • sheep(100568285) cytochrome P450, family 2, subfamily E, polypeptide 1
  • domestic cat(554344) cytochrome P450 2E1
  • dog(415128) cytochrome P450, family 2, subfamily E, polypeptide 1
  • cow(282213) cytochrome P450, family 2, subfamily E, polypeptide 1
  • Horse(100066422) cytochrome P450, family 2, subfamily E, polypeptide 1

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CYP2E1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-CYP2E1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-CYP2E1, affinity isolated antibody,
Reattività con
human
Applicazione
western blot
Anti-Cytochrome P450 Enzyme CYP2E1 Antibody, serum, Chemicon®,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot

Cell Lines

Numero di prodotto
Descrizione
Specie
CypExpress 2E1 Cytochrome P450 human, ,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
Cytochrome P450 human, 2E1 isozyme microsomes, with P450 Reductase and cytochrome b5, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CYP2E1,
Specie
human