DDIT3
DNA-damage-inducible transcript 3
Sinonimi:
CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
Specie:
Human DDIT3 (1649), Mouse Ddit3 (13198), Rat Ddit3 (29467), cow DDIT3 (777788), domestic guinea pig Ddit3 (101787388), chicken DDIT3 (100857832), Zebrafish ddit3 (561924), domestic cat DDIT3 (101081819), sheep DDIT3 (541600), dog DDIT3 (607439)
ID UniProtKB:
ID gene:
- Human(1649) Summary: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
- Mouse(13198) DNA-damage inducible transcript 3
- Rat(29467) DNA-damage inducible transcript 3
- cow(777788) DNA-damage-inducible transcript 3
- domestic guinea pig(101787388) DNA-damage-inducible transcript 3
- chicken(100857832) DNA-damage-inducible transcript 3
- Zebrafish(561924) DNA-damage-inducible transcript 3
- domestic cat(101081819) DNA-damage-inducible transcript 3
- sheep(541600) DNA-damage-inducible transcript 3
- dog(607439) DNA-damage-inducible transcript 3
- naked mole-rat(101715873) DNA-damage-inducible transcript 3
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-GADD153/DDIT3/CHOP Antibody, from rabbit, purified by affinity chromatography,
Reattività con
bovine, human, monkey, mouse, porcine, rat
Applicazione
western blot
Anti-CHOP, N-Terminal antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-DDIT3/CHOP antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Anti-DDIT3/CHOP antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GADD153/DDIT3 Antibody, clone 3I18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse, rat
Applicazione
ELISA
affinity binding assay
western blot
affinity binding assay
western blot