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Merck

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

Sinonimi:
ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2
Specie:
ID UniProtKB:
ID gene:
  • Human(5168) Summary: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
  • Mouse(18606) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Rat(84050) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • dog(482026) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • chicken(420361) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Zebrafish(393575) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • naked mole-rat(101710936) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic guinea pig(100722506) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • cow(532663) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • sheep(101120171) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic cat(101097620) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Horse(100057101) ectonucleotide pyrophosphatase/phosphodiesterase 2

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Autotaxin Antibody, from rabbit, purified by affinity chromatography,
Reattività con
bovine, canine, human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-Autotaxin (ENPP2) Antibody, clone 7A5, clone 7A5, from mouse,
Reattività con
human, mouse
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-ENPP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-ENPP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot

Proteins

Numero di prodotto
Descrizione
Specie
ENPP2, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human ENPP2,
Specie
human
MISSION® esiRNA, targeting mouse Enpp2,
Specie
mouse