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Merck

FANCD2

Fanconi anemia, complementation group D2

Sinonimi:
FA-D2, FA4, FACD, FAD, FAD2, FANCD
Specie:
Human FANCD2 (2177), Mouse Fancd2 (211651), Rat Fancd2 (312641), dog FANCD2 (484659), Horse FANCD2 (100051871), naked mole-rat Fancd2 (101705946), cow FANCD2 (515845), chicken FANCD2 (415935), Zebrafish fancd2 (394241), domestic guinea pig Fancd2 (100729511) ...Più
ID UniProtKB:
Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9
ID gene:
  • Human(2177) Summary: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(211651) Fanconi anemia, complementation group D2
  • Rat(312641) Fanconi anemia, complementation group D2
  • dog(484659) Fanconi anemia, complementation group D2
  • Horse(100051871) Fanconi anemia, complementation group D2
  • naked mole-rat(101705946) Fanconi anemia, complementation group D2
  • cow(515845) Fanconi anemia, complementation group D2
  • chicken(415935) Fanconi anemia, complementation group D2
  • Zebrafish(394241) Fanconi anemia, complementation group D2
  • domestic guinea pig(100729511) Fanconi anemia, complementation group D2
  • fruit fly(2768674) CG17269 gene product from transcript CG17269-RA
  • Domestic Rabbit(100346581) Fanconi anemia, complementation group D2
  • domestic cat(101092341) Fanconi anemia, complementation group D2
  • sheep(101123503) Fanconi anemia, complementation group D2

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
MABS1889
Anti-FANCD2 Antibody, clone 10F8.1, clone 10F8.1, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
western blot
HPA063742
Anti-FANCD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
SAB4503870
Anti-phospho-FANCD2 (pSer222) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
PLA0243
Rabbit anti-FANCD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reattività con
human
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
EHU029261
MISSION® esiRNA, targeting human FANCD2,
Specie
human
EMU207581
MISSION® esiRNA, targeting mouse Fancd2,
Specie
mouse