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Merck

FUT3

fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)

Sinonimi:
CD174, FT3B, FucT-III, LE, Les
Specie:
ID UniProtKB:
ID gene:
  • Human(2525) Summary: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
  • Thale Cress(843783) fucosyltransferase 3
  • sheep(101108745) fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
  • naked mole-rat(101727627) fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human Fucosyltransferase 3 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-FUT3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human FUT3,
Specie
human