Passa al contenuto
Merck

HDAC6

histone deacetylase 6

Sinonimi:
HD6
Specie:
ID UniProtKB:
ID gene:
  • Human(10013) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
  • Mouse(15185) histone deacetylase 6
  • Rat(84581) histone deacetylase 6
  • sheep(101109245) histone deacetylase 6
  • Zebrafish(565482) histone deacetylase 6
  • domestic guinea pig(100717988) histone deacetylase 6
  • dog(480907) histone deacetylase 6
  • fruit fly(32461) CG6170 gene product from transcript CG6170-RA
  • naked mole-rat(101708442) histone deacetylase 6
  • domestic cat(101084086) histone deacetylase 6
  • cow(513602) histone deacetylase 6

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Monoclonal Anti-HDAC6 antibody produced in mouse, clone 3A6, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot
Anti-HDAC6 Antibody, CT, Upstate®, from rabbit,
Reattività con
human, mouse
Applicazione
immunoprecipitation (IP)
western blot
Monoclonal Anti-HDAC6 antibody produced in mouse, clone 1E2, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-phospho-HDAC6 (pSer22) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
western blot
Anti-phospho-HDAC6 (pSer22) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
SAHA, ≥98% (HPLC),
Specie
human
Trichostatin A, ≥98% (HPLC), from Streptomyces sp.,
Specie
human, mouse, rat
Romidepsin, ≥98% (HPLC),
Specie
human
CI−994, ≥98% (HPLC), powder,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
HDAC-6 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Specie
human
HDAC6 H216A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE),
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human HDAC6,
Specie
human
MISSION® esiRNA, targeting mouse Hdac6,
Specie
mouse