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Merck

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

Sinonimi:
5-HT(2B), 5-HT2B
Specie:
Human HTR2B (3357), Mouse Htr2b (15559), Rat Htr2b (29581), chicken HTR2B (395581), Zebrafish htr2b (751784), dog HTR2B (403881), cow HTR2B (407135), Horse HTR2B (100057052), domestic cat HTR2B (101095762), Domestic Rabbit HTR2B (100343392) ...Più
ID UniProtKB:
P41595, B2R9D5, Q53TI1, Q62221, Q6P523
ID gene:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

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Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
B175
BW 723C86, ≥98% (HPLC),
Specie
human
Y0000776
Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,
Specie
human
1430000
Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Y0000777
Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Specie
human
M110
α-Methylserotonin maleate salt, ≥98% (HPLC),
Specie
human

Small Molecule - Allosteric Modulator

Numero di prodotto
Descrizione
Specie
D9190
DCEBIO, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
Y0000776
Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,
Specie
human
1430000
Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Y0000777
Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Specie
human
S006
Ketanserin (+)-tartrate salt, ≥97%, solid,
Specie
human
C4542
Cyclobenzaprine hydrochloride, ,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
SAB4501475
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence
immunohistochemistry
western blot
HPA063658
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
SAB4501476
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence
western blot
HPA012867
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
SAB2109002
Anti-HTR2B (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, canine, guinea pig, horse, human, mouse, pig
Applicazione
western blot

Small Molecule - Blocker

Numero di prodotto
Descrizione
Specie
M2525
Mianserin hydrochloride, ,
Specie
human
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Specie
human
Z101
Zimelidine dihydrochloride, solid,
Specie
human

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
N7261
Nortriptyline hydrochloride, ≥98% (HPLC), powder,
Specie
human
A129
Amoxapine, ,
Specie
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Specie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Specie
human
F132
Fluoxetine hydrochloride, solid,
Specie
human

Small Molecule - Ligand

Numero di prodotto
Descrizione
Specie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Specie
human

Small Molecule - Metabolite

Numero di prodotto
Descrizione
Specie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Specie
human

Small Molecule - Mixed Agonist/Antagonist

Numero di prodotto
Descrizione
Specie
M8046
Mifepristone, ≥98%,
Specie
human, mouse, rat
C6305
Clozapine, ,
Specie
human, rat

Small Molecule - Precursor

Numero di prodotto
Descrizione
Specie
H9772
5-Hydroxy-L-tryptophan, powder,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU052881
MISSION® esiRNA, targeting human HTR2B,
Specie
human